Immunodensity isolation of untouched myeloid cells for lineage-specific chimerism analysis.

• Fast and easy-to-use
• Requires no special equipment or training
• Isolated cells are untouched

The RosetteSep™ HLA Myeloid Cell Enrichment Cocktail is designed to enrich myeloid (CD33+) cells from whole blood by negative selection for lineage-specific chimerism analysis. Unwanted cells are targeted for removal with Tetrameric Antibody Complexes recognising CD3, CD8, CD19, CD56 and glycophorin A on red blood cells (RBCs). When centrifuged over a buoyant density medium such as RosetteSep™ DM-M (STMC15725), the unwanted cells pellet along with the RBCs. The purified myeloid cells are present as a highly enriched population at the interface between the plasma and the buoyant density medium. The desired cells are immediately ready for chimerism analysis or other downstream applications.

Please Note: In light of the new EU Regulation 2017/746 (IVDR) of the European Parliament and of the Council on in vitro diagnostic medical devices, which is expected to become effective in 2022, STEMCELL recently deregistered and removed the CE IVD claims associated with these products, and they are now labeled 'For Research Use Only'. Please note there have been no changes to the form, function and quality assurances associated with these products.