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Anti-Vimentin Mouse Monoclonal Antibody [clone: 1A7]
  STMC100-1065
 :  STEMCELL Technologies
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Anti-Vimentin Mouse Monoclonal Antibody [clone: 1A7]
  STMC100-1065
 :  STEMCELL Technologies

 

  • Antigen name:
    Vimentin
  • Clonality:
    Monoclonal
  • Clone:
    1A7
  • Host:
    Mouse
  • Isotype:
    IgG1 kappa
  • Reactivity:
    Human
  • Gene ID:
    7431
  • Pk:
    100 µG

 

 

Mouse monoclonal antibody against human, mouse, rat vimentin.

  • Intestinal cells

Clone1A7 is a mouse monoclonal antibody that reacts with human vimentin, a class III intermediate filament that is composed of α-helical regions linked into a coiled-coil protein and confers mechanical resistance in cells. Use the 1A7 clone in applications requiring detection of vimentin. It is verified for use with immunocytochemistry (ICC). Vimentin is expressed in mesenchymal cells and mediates several functions, including cell adhesion, signaling, and migration. Vimentin filaments have been reported to interact with signaling proteins, such as Cdc42, Rac1, and the 14-3-3 family of proteins, suggesting a role in modulation and regulation of signal transduction processes. This structural protein is also involved in the LARP-6 dependent binding and stabilization of collagen mRNA during the development of tissue fibrosis. It is regarded as a marker of mesenchymal-derived cells but has been implicated in tumor detection, such as in distinguishing between some sarcomas and carcinomas.

 : Product restrictions: (i) Customer shall not make products or any portion of them in any way, shape or form, including as a component of another product available for the purpose of further resale or alter or remove the Product label and the Supplier’s mark of origin without express written permission of Supplier and (ii) Customer is familiar with Supplier’s restrictions on the use of the products and shall use the products in compliance with such restrictions and the applicable Supplier Product Information sheet (collectively, the 'Product Restrictions').

Type:
Antigen: Vimentin
Clonality: Monoclonal
Clone: 1A7
Conjugation:
Epitope:
Host: Mouse
Isotype: IgG1 kappa
Reactivity: Human