Anti-SHIP Rabbit Polyclonal Antibody

STMC60144

: STEMCELL Technologies

Anti-SHIP Rabbit Polyclonal Antibody

STMC60144

: STEMCELL Technologies

Antigen name:
SHIP
Clonality:
Polyclonal
Conjugation:
Unconjugated
Host:
Rabbit
Reactivity:
Human,
Mouse
Gene ID:
3635 (human), 16331 (mouse)
Pk:
100 µl

Rabbit polyclonal antibody against human, mouse SHIP, unconjugated.

Granulocytes
Subsets
Lymphocytes
Myeloid cells

The SH2-containing inositol phosphatase (SHIP, also called SHIP1) is a 145 kDa hematopoietic-restricted protein that becomes tyrosine-phosphorylated and associated with the adaptor protein, Shc, following cytokine, growth factor, chemokine, and immunoreceptor stimulation. SHIP also hydrolyzes the critical phosphatidylinositol (PI)-3-kinase (PI3K)-generated second messenger, PI-3,4,5-P3 (PIP3), to PI-3,4-P2 1,2 and therefore acts as an important negative regulator of the PI3K pathway. This antibody reacts with mouse and human full-length 145 kDa SHIP protein.

: Product restrictions: (i) Customer shall not make products or any portion of them in any way, shape or form, including as a component of another product available for the purpose of further resale or alter or remove the Product label and the Supplier’s mark of origin without express written permission of Supplier and (ii) Customer is familiar with Supplier’s restrictions on the use of the products and shall use the products in compliance with such restrictions and the applicable Supplier Product Information sheet (collectively, the 'Product Restrictions').

Type:
Antigen: SHIP
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype:
Reactivity: Human;Mouse