Anti-TRA-2-49 Mouse Monoclonal Antibody [clone: TRA-2-49/6E]

Catalog # STMC60066

Supplier: STEMCELL Technologies

Catalog # STMC60066

Supplier: STEMCELL Technologies

Specifications

Antigen name:
TRA-2-49
Clonality:
Monoclonal
Clone:
TRA-2-49/6E
Conjugation:
Unconjugated
Host:
Mouse
Isotype:
IgG1 kappa
Reactivity:
Pig,
Rabbit,
Non-human primates,
Human,
Cat
Gene ID:
249
Size:
100 μg
Pk:
0,2 mL

Specifications

About this item

Mouse monoclonal IgG1 antibody against human, chimpanzee, gibbon TRA-2-49 (tissue non-specific alkaline phosphatase), unconjugated.

Pluripotent stem cells

The TRA-2-49/6E antibody reacts with the tissue non-specific isoform of alkaline phosphatase (AP), which is expressed at high levels in undifferentiated pluripotent stem cells such as human and mouse embryonic stem (ES) cells, as well as induced pluripotent stem (iPS) and embryonal carcinoma (EC) cells. This isozyme of AP is the same as that expressed by liver, bone and kidney cells. Levels of AP decrease upon differentiation and, thus, the TRA-2-49/6E antibody can be used to monitor the differentiation status of pluripotent stem cells. The TRA-2-49/6E antibody does not cross-react with other isozymes of AP, which differ through post-translational modification, and reportedly does not recognise AP from cow, dog, goat, Guinea pig, hamster, mouse, rat or sheep, or Old World Monkeys such as the rhesus monkey, baboon and African green monkey.

Caution: Product restrictions: (i) Customer shall not make products or any portion of them in any way, shape or form, including as a component of another product available for the purpose of further resale or alter or remove the Product label and the Supplier’s mark of origin without express written permission of Supplier and (ii) Customer is familiar with Supplier’s restrictions on the use of the products and shall use the products in compliance with such restrictions and the applicable Supplier Product Information sheet (collectively, the 'Product Restrictions').

Type:
Antigen: TRA-2-49
Clonality: Monoclonal
Clone: TRA-2-49/6E
Conjugation: Unconjugated
Epitope:
Host: Mouse
Isotype: IgG1 kappa
Reactivity: Cat, Human, Non-Human Primate, Pig, Rabbit