Anti-Villin 1 Rabbit Polyclonal Antibody

STMC100-1066

: STEMCELL Technologies

STMC100-1066

: STEMCELL Technologies

Antigen name:
Villin 1
Clonality:
Polyclonal
Vært:
Rabbit
Reactivity:
Human
Gen ID:
7429
Pakn:
100 µl

Rabbit polyclonal antibody against human villin 1.

Intestinal cells

This rabbit polyclonal antibody reacts with human villin 1, a calcium-regulated protein expressed in epithelial cells. Villin 1 is organized into six conserved domains, which make up the villin core, and a C-terminal headpiece domain, which contains an F-actin binding site. Use this polyclonal antibody in applications requiring detection of villin 1, such as western blotting (WB) assays and immunohistochemistry (IHC). It is verified for use with immunocytochemistry (ICC). Villin 1 is an important player in the reorganization of microvillar actin filaments and is involved in actin nucleation, polymerization, and severing. It is a key component in the growth and development of intestinal epithelial cells, regulating cell morphology, growth, and apoptosis. Villin 1 has been suggested as a predictive factor in some adenocarcinomas of the endocervix, colon, and lungs. Abnormal villin expression has also been associated with biliary atresia and cholestasis.

: Product restrictions: (i) Customer shall not make products or any portion of them in any way, shape or form, including as a component of another product available for the purpose of further resale or alter or remove the Product label and the Supplier’s mark of origin without express written permission of Supplier and (ii) Customer is familiar with Supplier’s restrictions on the use of the products and shall use the products in compliance with such restrictions and the applicable Supplier Product Information sheet (collectively, the 'Product Restrictions').

Type:
Antigen: Villin 1
Clonality: Polyclonal
Clone:
Conjugation:
Epitope:
Host: Rabbit
Isotype:
Reactivity: Human