Anti-UNC13B Rabbit Polyclonal Antibody
Catalog # PRSI56-860
Supplier: ProSci Inc.
Specifications
- Antibody type:Primary
- Antigen name:Protein unc-13 homolog B
- Antigen symbol:UNC13B
- Clonality:Polyclonal
- Conjugation:Unconjugated
- Host:Rabbit
- Reactivity:Mouse
- Western blot:Yes
- Epitope:Amino acid range = 263-292
- Form:Liquid
- Gene ID:O14795
- Modification:None
- Storage buffer:Supplied in PBS with 0,09% (W/V) sodium azide
- Molecular weight:181 kDa
- Storage temperature:Store at 4 °C for three months and –20 °C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
- Concentration:0,45 mg/ml
- Shipping temperature:4 °C
- Immunogen:This UNC13B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 263-292 amino acids from the N-terminal region of human UNC13B
- Purification:This antibody is purified through a protein A column, followed by peptide affinity purification
- Pk:400 µl
Specifications
About this item
This gene is expressed in the kidney cortical epithelial cells and is upregulated by hyperglycemia. The encoded protein shares a high level of similarity to the rat homolog, and contains 3 C2 domains and a diacylglycerol-binding C1 domain. Hyperglycemia increases the levels of diacylglycerol, which has been shown to induce apoptosis in cells transfected with this gene and thus contribute to the renal cell complications of hyperglycemia. Studies in other species also indicate a role for this protein in the priming step of synaptic vesicle exocytosis. [provided by RefSeq].
- For WB starting dilution is: 1:1000
Type: Primary
Antigen: UNC13B
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype: Rabbit Ig
Reactivity: Mouse