Human Recombinant SCF

ORIGTP723730

Human Recombinant SCF

ORIGTP723730

Pk:
10 µG
Protein/peptide type:
Recombinant
Species:
Human
Storage conditions:
Store at −80 °C.
Endotoxin content:
Less than 0,01 ng per µg protein as determined by the LAL method.
Biological activity:
The ED50 is 3 - 12 ng/ml, corresponding to a specific activity of 0,8 - 3,3×10⁵ units/mg, determined by TF-1 cell proliferation induced in a dose dependent manner.
Endotoxin-free:
Yes
Protein synonyms:
FPHH|SLF|KL-1|Kitl|DFNA69|DCUA|SF|FPH2|MGF|SHEP7
Protein/peptide name:
SCF
Purity:
>98%, as determined by Coomassie stained SDS-PAGE.
Molecular weight:
18,6 kDa
Concentration:
Lot specific

This gene encodes the ligand of the tyrosine-kinase receptor encoded by the KIT locus. This ligand is a pleiotropic factor that acts in utero in germ cell and neural cell development, and hematopoiesis, all believed to reflect a role in cell migration. In adults, it functions pleiotropically, while mostly noted for its continued requirement in hematopoiesis. Two transcript variants encoding different isoforms have been found for this gene. (provided by RefSeq, Jul 2008).