Dog Recombinant RC GM-CSF (Animal free) (from E. coli)

Vascular endothelial growth factor-A (VEGF-A) is produced by a wide variety of cell types, including tumor and vascular cells. VEGF-A is a mediator of vascular growth, vascular permeability, and plays a role in stimulating vasodilation via nitric oxide-dependent pathways. VEGF-A has several alternatively spliced isoforms, with VEGF-165 being the most abundant. The VEGF-165 isoform is a secreted protein that acts on receptors VEGFR-1 and VEGFR-2 to modulate endothelial cell proliferation and angiogenesis.

High quality
Low endotoxin
Affordable

Animal-free proteins are ideal for researchers concerned about the ever-present risk of contaminating human proteins or trace growth factors from FBS and animal-derived ingredients typically used in standard recombinant protein production techniques.

: A certificate of analysis (COA) is supplied with each product shipped detailing purity, formulation, biological activity, endotoxin levels, reconstitution instructions and recommended storage conditions.

: For research use only.

Conjugation:
Unconjugated
Protein function:
Cytokine
Protein/peptide type:
Recombinant
Source:
E. coli
Species:
Dog
Storage conditions:
−20 °C
Endotoxin content:
Endotoxin LAL (EU/µg) ≤0.1
Biological activity:
Bioactivity assay: TF-1 cell proliferation, ED50 ≤15 ng/ml, bioactivity ≥6,7×10⁴ units/mg
Gene ID:
P48749
Reconstitution instructions:
Sterile water at 0,1 mg/ml
Endotoxin-free:
N
Carrier-free:
Y
Protease-free:
N
Animal-free:
Y
Protein synonyms:
MGI-1GM|CSF-2|Pluripoietin-α
UniProtKB:
P48749
Protein/peptide name:
GM-CSF
Purity:
≥95%
Molecular weight:
14,4 kDa
Sequence:
MAPTRSPTLV TRPSQHVDAI QEALSLLNNS NDVTAVMNKA VKVVSEVFDP EGPTCLETRL QLYKEGLQGS LTSLKNPLTM MANHYKQHCP PTPESPCATQ NINFKSFKEN LKDFLFNIPF DCWKPVKK
Endotoxin level:
Low
Formulation:
10 mM sodium phosphate, pH 7,5
Nuclease-free:
N
Grade:
RUO
Shipping temperature:
RT
Tested applications:
Bioassay