Mouse recombinant complement factor D
PRSI92-692
:
- Pk:50 µG
- Protein/peptide type:Recombinant
- Species:Mouse
- Tag sequence:C-10 His tag
- Storage conditions:Lyophilized protein should be stored at −20 °C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7 °C for 2-7 days. Aliquots of reconstituted samples are stable at −20 °C for 3 months.
- Protein synonyms:Df|Properdin factor D|28 kDa adipocyte protein|Complement factor D|C3 convertase activator|Adn|Adipsin|Cfd
- Protein/peptide name:Complement factor D
- Purity:> 95% as determined by reducing SDS-PAGE
- Molecular weight:26.8 kD
- Sequence:Ile26-Ser259
- Formulation:Lyophilized from a 0.2 um filtered solution of 20mMTris,150mMNaCl,pH7.5. Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 ug/ml. Dissolve the Lyophilized protein in ddH2O. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
Complement factor D, also known as adipsin, is a member of the chymotrypsin family of serine proteases, which plays an essential role in host defence as the rate-limiting enzyme in the alternative pathway of complement activation. Complement factor D activates a convertase (C3bBb) responsible for cleavage of the complement protein C3, which leads to the activation of terminal complement component C5-9 to form the membrane attack complex on microbial or cellular surfaces. It also functions in the regulation of systemic energy balance and physiologic and pathologic processes, including immunity and inflammation.
Fusion-Tag: C-10 His tag
This recombinant protein can be used for biological assays. For research use only.