Specifications
- Pk:50 µG
- Protein/peptide type:Recombinant
- Species:Mouse
- Tag sequence:C-6 His tag
- Storage conditions:Lyophilized protein should be stored at −20 °C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7 °C for 2-7 days. Aliquots of reconstituted samples are stable at −20 °C for 3 months.
- Protein synonyms:MGC88159|9.5S alpha-1-glycoprotein|PTX2serum amyloid P-component|SAP|Serum amyloid P|APCS|PTX2|SAP pentaxin-related
- Protein/peptide name:Pentraxin 2
- Purity:> 95% as determined by reducing SDS-PAGE
- Molecular weight:24.9 kD
- Sequence:Gln21-Asp224
- Formulation:Lyophilized from a 0.2 um filtered solution of PBS,pH7.4. Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 ug/ml. Dissolve the Lyophilized protein in ddH2O. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
Specifications
About this item
Pentraxin 2 (PTX2), also known as Serum amyloid P (SAP), is a highly conserved, naturally circulating plasma protein and a soluble pattern recognition receptor of the innate immune system. The unique binding activities indicated that it may play an important role in the removal of damaged tissue. PTX2 belongs to the pentraxin family, is universally present in amyloid deposits. Mouse with targeted deletion of the PTX2 gene shows retarded and reduced induction of experimental reactive systemic (AA type) amyloidosis confirmed that it does indeed contribute to pathogenesis of amyloidosis and is a valid therapeutic target. In recent discovery, PTX2 can be used as a powerful antifibrotic agent to regulate certain monocyte differentiation states.
- This recombinant protein can be used for biological assays. For research use only.
Fusion-Tag: C-6 His tag
This recombinant protein can be used for biological assays. For research use only.