- Pakn:50 µG
- Protein/peptide type:Recombinant
- Kilde:E. coli
- Species:Human
- Environmentally Preferable:
- Storage conditions:Lyophilized protein should be stored at −20 °C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7 °C for 2-7 days. Aliquots of reconstituted samples are stable at −20 °C for 3 months.
- Protein synonyms:NDF|EGF|NRG1-beta 1|SMDF|Pro-neuregulin-1|HRG1‑beta 1|NRG1|HRG1-beta 1|GGF|Neuregulin-1 beta 1|HRGA|HGL
- Protein/peptide name:NRG1 beta 1
- Renhed:> 95% as determined by reducing SDS-PAGE
- Molecular weight:7.5 kD
- Sekvens:Ser177-Glu241
- Formulering:Lyophilized from a 0.2 um filtered solution of PBS,pH7.4. Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 ug/ml. Dissolve the Lyophilized protein in ddH2O. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
- Tested applications:Bioassay
neuregulin-1 (heregulin-1，NRG1) is a member of neuregulin family, which is comprised of four genes that encode a large number of secreted or membrane-bound isoforms. All family members share an EGF-like domain that interacts with the ErbB family of tyrosine kinase receptors. NRG1 isoforms can be classified into type I, type II and type III isoforms. NRG1 directs ligand for ERBB3 and ERBB4 tyrosine kinase receptors, concomitantly recruits ERBB1 and ERBB2 coreceptors, resulting in ligand-stimulated tyrosine phosphorylation and activation of the ERBB receptors. NRG proteins show distinct spatial and temporal expression patterns and play important roles during development of both the nervous system and the heart.
This recombinant protein can be used for biological assays. For research use only.