Human recombinant S100A8 & S100A9 heterodimer (from E. coli)
Catalog # PRSI91-638
Supplier: ProSci Inc.
CAS Number:
Specifications
- Pk:50 µG
- Protein/peptide type:Recombinant
- Source:E. coli
- Species:Human
- Tag sequence:C-6 His tag
- Storage conditions:Store at −20 °C, stable for 6 months after receipt. Please minimize freeze-thaw cycles.
- Protein synonyms:S100A8/S100A9 Heterodimer
- Protein/peptide name:S100A8 & S100A9 Heterodimer
- Purity:> 95% as determined by reducing SDS-PAGE
- Molecular weight:11.7 and 13.2 kD
- Sequence:Met1-Glu93(S100A8
- Formulation:Supplied as a 0.2 um filtered solution of 20mM HEPES,10%Glycerol,150mM NaCl,2.5mM EDTA,pH 7.4. Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 ug/ml. Dissolve the lyophilized protein in ddH2O. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
Specifications
About this item
S100A8 is a member of the S100 family, EF-hand superfamily of Ca-binding proteins. It is produced by neutrophils and monocytes, and forms Ca2+-dependent heterodimer/heterotetramer complexes (termed calprotectin) with S100A9. Calprotectin (S100A8/A9) which has a wide plethora of intra- and extracellular functions. The intracellular functions include: facilitating leukocyte arachidonic acid trafficking and metabolism, modulation of the tubulin-dependent cytoskeleton during migration of phagocytes and activation of the neutrophilic NADPH-oxidase.
- This recombinant protein can be used for biological assays. For research use only.
Fusion-Tag: C-6 His tag