Human recombinant FGF Acidic (from E. coli)
Catalog # PRSI40-588
Supplier: ProSci Inc.
CAS Number:
Specifications
- Pk:50 µG
- Protein/peptide type:Recombinant
- Source:E. coli
- Species:Human
- Environmentally Preferable:
- Biological activity:Assay #1: The ED50 as determined by the dose-dependent stimulation of thymidine uptake by BaF3 cells expressing FGF receptors is = 10 ng/mL corresponding to a specific activity of = 1 x 105 units/mg.
Assay #2: The ED50 was determined by a cell proliferation assay using balb/c 3T3 cells is = 0.5 ng/mL in the presence of 10 μg/mL heparin, corresponding to a specific activity of = 2 x 106 units/mg. - Protein synonyms:Acidic fibroblast growth factor|Fgf-1|Dffrx|Fgfa|Fibroblast growth factor 1|Fam|FGF-1
- Protein/peptide name:FGF Acidic
- Purity:>95%
- Formulation:Lyophilized
Specifications
About this item
FGF-acidic is one of 23 known members of the FGF family. Proteins of this family play a central role during prenatal development and postnatal growth and regeneration of a variety of tissues, by promoting cellular proliferation and differentiation. FGF-acidic is a non-glycosylated heparin binding growth factor that is expressed in the brain, kidney, retina, smooth muscle cells, bone matrix, osteoblasts, astrocytes and endothelial cells. FGF-acidic has the ability to signal through all the FGF receptors. Recombinant murine FGF-acidic is a 15.9 kDa protein consisting of 141 amino acid residues.
- Store in working aliquots at -20°C. Avoid freeze/thaw cycles.