This MAb reacts with a 58 kDa protein identified as vimentin. It shows no cross-reaction with other closely related intermediate filament proteins (IFP s) such as desmin, keratin, neurofilament, and glial fibrillary acid protein.Anti-vimentin alone is of limited value as a diagnostic tool; however, when used in panels with other antibodies, it is useful for the sub-classification of a given tumor. Expression of vimentin, when used in conjunction with anti-keratin, is helpful when distinguishing melanomas from undifferentiated carcinomas and large cell lymphomas. All melanomas and Schwannomas react strongly with anti-vimentin. It labels a variety of mesenchymal cells, including melanocytes, lymphocytes, endothelial cells, and fibroblasts. Non-reactivity of anti-vimentin is often considered more useful than its positive reactivity, since there are a few tumors that do not contain vimentin, e.g. hepatoma and seminoma. Anti-vimentin is also useful as a tissue process control reagent.
Type: Primary
Antigen: VIM
Clonality: Monoclonal
Clone: VM1170
Conjugation: CF640R
Epitope:
Host: Mouse
Isotype: IgG1
Reactivity: Human
- Catalog No:
- BNC401170-100
- BNC401170-500
- Antigen symbol:
- VIM
- VIM
- Antigen name:
- Vimentin
- Vimentin
- Antigen synonyms:
- VIM
- VIM
- Antibody type:
- Primary
- Primary
- Clonality:
- Monoclonal
- Monoclonal
- Conjugation:
- CF® 640R
- CF® 640R
- Clone:
- Clone VM1170
- Clone VM1170
- Reactivity:
- Human
- Human
- Host:
- Mouse
- Mouse
- Gene ID:
- 455493
- 455493
- Isotype:
- IgG1
- IgG1
- Western blot:
- Yes
- Yes
- ImmunoChemistry:
- Yes
- Yes
- ImmunoFluorescence:
- Yes
- Concentration:
- 0,1 mg/ml
- 0,1 mg/ml
- Storage buffer:
- PBS/0,1% BSA/0,05% azide
- PBS/0,1% BSA/0,05% azide
: VWR Chemicals
: VWR Collection
: KIMBERLY CLARK
: VWR Chemicals
: VWR Collection
: VWR Collection
: VWR Collection
: VWR Collection