Anti-PS1 + PS2 Rabbit Polyclonal Antibody
BOSSBS-11681R
: Bioss
- Antistof type:Primary
- Antigen name:Presenilin 1 + 2
- Antigen symbol:PS1 + PS2
- Clonality:Polyclonal
- Konjugation:Unconjugated
- Vært:Rabbit
- ImmunoChemistry:Yes
- Isotype:IgG
- Reactivity:Human,Rat,Mouse
- Western blot:Yes
- Environmentally Preferable:
- Form:liquid
- Antigen synonymer:PS2|AD 3|FAD|AD4|Alzheimer disease 3|Presenilin 2|Presenilin 1|PS-2|PS1|PSEN2|Presenilin-1|PSN1_HUMAN|PSEN1|Alzheimer disease 4|PSN2_HUMAN.|STM2|PS-1|Presenilin1|AD5|Presenilin-2
- Storage buffer:Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0,09% sodium azide. Store at -20°C for 12 months.
- Koncentration:1 ug/ul
- Shipping temperature:4 °C
- Purification:Purified by Protein A.
- Størrelse:100 μg
- Pakn:100 µl
Alzheimer's disease (AD) patients with an inherited form of the disease carry mutations in the presenilin proteins (PSEN1; PSEN2) or the amyloid precursor protein (APP). These disease-linked mutations result in increased production of the longer form of amyloid-beta (main component of amyloid deposits found in AD brains). Presenilins are postulated to regulate APP processing through their effects on gamma-secretase, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors and APP.
WB(1:100-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200)
Type: Primary
Antigen: PS1 + PS2
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat