You searched for: Sorafenib (BAY 43-9006)

Supplier: Apollo Scientific

Sorafenib is a multikinase inhibitor of Raf-1 B-Raf and VEGFR-2 with IC50 of 6 nM 22 nM and 90 nM in cell-free assays respectively.

Supplier: Abcam

Potent multikinase inhibitor that targets the RAF/MEK/ERK pathway in tumor cells, and tyrosine kinases involved in tumor angiogenesis, oncogenesis, and maintenance of the tumor microenvironment. Inhibits Raf-1, B-Raf, VEGFR-2, VEGFR-3, PDGFR-β, Flt3, c-KIT and FGFR-1 (IC₅₀ values are 6, 22, 90, 20, 57, 58, 68 and 580 nM in cell-free assays, respectively).