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3 resultater for Indirubin-3'-oxime | Avantor

Indirubin-3'-oxime

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3-(Hydroxyimino)-[2,3’-Biindolinylidene]-2’-One

Supplier: Apollo Scientific

3-(Hydroxyimino)-[2,3’-Biindolinylidene]-2’-One

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Indirubin-3'-monoxime

Supplier: Apollo Scientific

Indirubin-3'-monoxime

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Indirubin-3'-oxime

Supplier: Abcam

Potent GSK3β inhibitor (IC₅₀ =22 nM). CDK inhibitor (IC₅₀ values are 0,1 (Cdk5/p35), 0,18 (Cdk1/cyclin B), 0,25 (Cdk2/cyclin E), 0,5 (Cdk2/cyclin A) and 3,3 μM (Cdk4/cyclin D1)). Shows reversible antiproliferative effects via G₂/M cell cycle arrest. Prevents tau phosphorylation. Shows neuroprotective effects in vivo.

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