Precolumn filters are essential for protecting HPLC columns against particulate matter which can accumulate on the column frit, leading to split peaks and high backpressure. Sources of particles include mobile phases (especially when buffers are mixed with organic solvents), leaking pump and injector seals, and samples. Precolumn filters are also useful because changing the column frit is extremely difficult to do without disturbing the column packing, whereas changing the precolumn filter’s frit is easy, providing relatively inexpensive insurance against column damage.

PEEK-encased frits

Supplier: VICI JOUR RESEARCH

Made of stainless steel or titanium. Titanium frits are resistant to corrosion, biocompatible and recommended for protein analysis.

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Stainless steel semi-prep frits, Upchurch Scientific®

Supplier: UPCHURCH SCIENTIFIC

Upchurch Scientific®, A-122 semi-prep frit, Porosity: 20,0 µm, Thickness: 1,6 mm, Frit Ø ext.: 4, 8 mm, Frit volume: 9,7 µl, Frit material: Stainless steel, Ring ext. Ø: 6,5 mm, Ring material: PCTFE

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PEEK frits, Upchurch Scientific®

Supplier: UPCHURCH SCIENTIFIC

Exceptionally uniform porosity which ensures longer filtration life and consistent frit-to-frit swept volumes. These frits are biocompatible and inert to most solvents, making them ideal for bioanalytical applications. The disc rings, made of PCTFE, are slightly thicker than the frit disc, providing enhanced sealing and excellent chemical resistance.

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Precolumn filters, high pressure

Supplier: VICI JOUR RESEARCH

Precolumn filter kit has a standard 10 to 32 fitting and fits direct to most column types without introducing an additional dead volume.

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Precolumn filters

Supplier: VICI JOUR RESEARCH

Precolumn filter, Stainless steel, Porosity: 2,0 µm, 1000 bar, Swept volume: 0,68 µl

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Stainless steel frits

Supplier: UPCHURCH SCIENTIFIC

Upchurch Scientific®, A-418 frit, Porosity: 0,5 µm, Thickness: 1,57 mm, Frit Ø ext.: 1,6 mm, Frit volume: 0,6 µl, Frit material: Stainless steel, Ring ext. Ø: 5,08 mm, Ring material: PCTFE