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Mouse recombinant CREB-binding highly active (from insect cells (Sf21))
Mouse recombinant CREB-binding highly active (from insect cells (Sf21))
Catalog # PRSI90-344
Supplier:  ProSci Inc.
CAS Number:  
Mouse recombinant CREB-binding highly active (from insect cells (Sf21))
Catalog # PRSI90-344
Supplier:  ProSci Inc.
CAS Number:  

Specifications

  • Pk:
    2 µG
  • Protein/peptide type:
    Recombinant
  • Source:
    Insect cells (Sf21)
  • Species:
    Mouse
  • Tag sequence:
    His Tag
  • Storage conditions:
    Stable for at least 6 months after receipt when stored at −80 °C.
  • Biological activity:
    ~50-100ng are required for standard HAT assay.
  • Protein synonyms:
    CBP|CREBBP
  • Protein/peptide name:
    CREB-binding highly active
  • Purity:
    >95% (SDS-PAGE)
  • Formulation:
    Liquid, In 50mM TRIS-HCl, pH 7.5, containing 100mM sodium chloride, 0.2% NP-40, 50-100mM imidazole and 10% glycerol.

Specifications

About this item

CREB-binding protein acetylates histones, giving a specific tag for transcriptional activation. It also acetylates non-histone proteins, like NCOA3 and FOXO1. It binds specifically to phosphorylated CREB and enhances its transcriptional activity toward cAMP-responsive genes. Acts as a coactivator of ALX1 in the presence of EP300.

Fusion-Tag: His Tag

This recombinant proteins is for research use only.

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