- Antibody type:Primary
- Antigen name:Polymerase (DNA Directed) Kappa
- Antigen symbol:POLK
- Clonality:Polyclonal
- Conjugation:Alexa Fluor® 555
- Host:Rabbit
- ImmunoChemistry:Yes
- Isotype:IgG
- Reactivity:Human,Rat,Mouse
- Environmentally Preferable:
- Cross adsorption:No
- Form:liquid
- Gene ID:27343
- Antigen synonyms:OTTHUMP00000020323|BETAN|BETA-N|POLL|DNA polymerase beta-2|pol lambda|polymerase (DNA-directed)|pol beta2|DNA-directed DNA polymerase lambda|POLKAPPA|polymerase (DNA directed)|DNA polymerase kappa (DNA polymerase beta-N)|POL-KAPPA|DNA polymerase lamda2|lambda|FLJ46002|RP11-529I10.1
- Storage buffer:Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at 4°C for 12 months.
- Storage temperature:Store at 4°C for 12 months
- Concentration:1 μg/μl
- Shipping temperature:4°C
- Purification:Purified by Protein A
- Pk:100 µl
DNA polymerase lambda (pol lambda), also designated DNA polymerase lambda or Pol Beta2, is a low-fidelity polymerase which plays a role in both spontaneous and DNA damage-induced mutagenesis. Encoded by the POLL gene, pol lambda is a member of the DNA polymerase type-X family. Pol lambda extends primer-terminal mispairs opposite nondamaged DNA templates, suggesting that it may assist in extending mismatched base pairs during normal DNA replication. In addition, pol ?may play a role in the mutagenic bypass of T-T dimers. Proliferating cell nuclear antigen (PCNA), a protein essential to DNA replication, interacts with pol lambda and thus influences the ability of pol ?to synthesize DNA.
Recommended Dilutions: IF(IHC-P): 1:50-200
Type: Primary
Antigen: POLK
Clonality: Polyclonal
Clone:
Conjugation: Alexa Fluor® 555
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat
: VWR Chemicals
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: KIMBERLY CLARK
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: VWR Collection
: VWR Collection