"Charles River Laboratories Cell Solutions"

Supplier: Charles River Laboratories Cell Solutions

Human peripheral blood CD14⁺ monocytes are isolated from peripheral blood mononuclear cells (PBMCs) by either positive or negative selection using immunomagnetic cell separation procedures. Peripheral blood cells are collected from normal human volunteers by direct collection or by using the COBE® Spectra or Spectra Optia® Apheresis System where cell-rich leukapheresis product is extracted using continuous flow centrifugal technology directly into the collection bag.

Supplier: Charles River Laboratories Cell Solutions

Mononuclear cells used for researching the causes, diagnosis, supportive care and treatment of Diabetes Mellitus 2 (DM2), the most common form of diabetes. Human mononuclear cells are collected from human volunteer donors diagnosed with DM2 under IRB approved informed consent by whole blood or leukapheresis using the COBE® Spectra Apheresis System MNC collection protocol.

Supplier: Charles River Laboratories Cell Solutions

Human mononuclear cells are isolated from IRB-consented volunteer donors diagnosed with HIV or AIDS.

Supplier: Charles River Laboratories Cell Solutions

A Leukopak is an enriched leukapheresis product collected from normal peripheral blood. It is composed of a variety of blood cells including monocytes, lymphocytes, platelets, plasma, and red cells. A leukopak contains a higher concentration of cells as compared to standard venipuncture collection methods or buffy coat products.

Supplier: Charles River Laboratories Cell Solutions

CryoStor® cryopreservation freeze media products have been designed to mitigate temperature-induced molecular cell stress responses during freezing and thawing.

Supplier: Charles River Laboratories Cell Solutions

CD8⁺ cytotoxic T cells are isolated from mononuclear cells by positive selection using immunomagnetic cell separation procedures.

Supplier: Charles River Laboratories Cell Solutions

Naive T cells are isolated by depleting CD45RO^₊ cells via immunomagnetic bead separation from a freshly collected leukopheresis product. Naive T cells are phenotypically classified as CD45⁺, CD^₊, and CD45RA^₊.

Supplier: Charles River Laboratories Cell Solutions

Human peripheral blood plasma used for researching the causes, diagnosis, supportive care and treatment of Crohn's disease (CD). Collected from IRB-consented donors diagnosed with CD.

Supplier: Charles River Laboratories Cell Solutions

CD4⁺/CD25⁺ regulatory T cells were isolated from leukapheresis product by CD127 depletion and positive selection using CD25 immunomagnetic beads. Peripheral blood cells are collected from normal human volunteers by direct collection or by using the COBE® Spectra or Spectra Optia® Apheresis System where cell-rich leukapheresis product is extracted using continuous flow centrifugal technology directly into the collection bag.

Supplier: Charles River Laboratories Cell Solutions

Human peripheral blood plasma used for researching the causes, diagnosis, supportive care and treatment of chronic myeloid leukemia (CML). Collected from IRB consented chronic myeloid leukemia (CML) disease donors.

Supplier: Charles River Laboratories Cell Solutions

CD34⁺ cells are isolated using positive immunomagnetic cell separation procedures from bone marrow. Bone marrow aspirates and cells, drawn from the posterior iliac crest using a syringe containing anticoagulant, are collected from normal human volunteers using institutional review board (IRB) approved procedures.

Supplier: Charles River Laboratories Cell Solutions

Human serum used for researching the causes, diagnosis, supportive care and treatment of multiple sclerosis (MS). Collected from IRB-consented donors diagnosed with MS.

Supplier: Charles River Laboratories Cell Solutions

Dendritic cells are obtained from a leukapheresis product using immunomagnetic separation techniques.

Supplier: Charles River Laboratories Cell Solutions

Mononuclear cells (MNCs) used for researching the causes, diagnosis, supportive care and treatment of Hepatitis C Virus (HCV). Human mononuclear cells are collected from human volunteer donors diagnosed with Hepatitis C virus under IRB approved informed consent.

Supplier: Charles River Laboratories Cell Solutions

Human peripheral blood M1 macrophages are derived from purified monocytes. CD14⁺ monocytes were isolated from peripheral blood mononuclear cells (PBMCs) using positive immunomagnetic cell separation procedures and were cultured in the presence of GM-CSF for 10 days. The M1 phenotyping was confirmed by morphology and the expression of specific biomarkers.

Supplier: Charles River Laboratories Cell Solutions

Human peripheral blood plasma used for researching the causes, diagnosis, supportive care and treatment of multiple sclerosis (MS). Collected from IRB-consented donors diagnosed with MS.