"Cayman Chemical"
Latrunculin A
Supplier: Cayman Chemical
Latrunculin A is a bioactive 2-thiazolidinone macrolide derived from sponges that sequesters G-actin and prevents F-actin assembly. It binds monomeric actin with 1:1 stoichiometry and can be used to block actin polymerization both in vitro (Kd = 0,2 μM) and in cells (0,5 μM, 30 min).
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Anti-Vtg Mouse Monoclonal Antibody [clone: ND-1E8]
Supplier: Cayman Chemical
Anti-Vtg Mouse Monoclonal Antibody [clone: ND-1E8]
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Butyrolactone 3 ≥95%, crystalline solid
Supplier: Cayman Chemical
Butyrolactone 3 specifically inhibits the histone acetyltransferase Gcn5 with an IC50 value of 100 μM and has an affinity to the Gcn5 enzyme comparable to that of its natural substrate, histone H3. Butyrolactone 3 can inhibit pre-RNA splicing with an IC50 value of 0,5 mM and as such has been used to investigate Gcn5/PCAF-like HAT functions during assembly of spliceosome before pre-mRNA translation.
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Q-VD-OPh
Supplier: Cayman Chemical
Q-VD-OPH is a broad-spectrum caspase inhibitor, blocking caspases-3, -7, -8, -9, -10, and -12 and inhibiting apoptosis when used at 10 µm. It more effectively inhibits apoptosis and is much less cytotoxic than Z-VAD-FMK and Boc-D-FMK.
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Anti-FTO Mouse Monoclonal Antibody [clone: FT 86-4]
Supplier: Cayman Chemical
Anti-FTO Mouse Monoclonal Antibody [clone: FT 86-4]
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Anti-5-LO Rabbit Polyclonal Antibody
Supplier: Cayman Chemical
Anti-5-LO Rabbit Polyclonal Antibody
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(-)-Indolactam V ≥97%, solid
Supplier: Cayman Chemical
(−)-Indolactam V is a tumor-promoting teleocidin compound that activates protein kinase C (PKC). It binds to PKC regulatory domains of mouse skin PKCη and rat brain PKCγ with Ki values of 3,4 nM and 1 μM, respectively. At 1 μM, (−)-indolactam V induces differentiation of human embryonic stem cells into pancreatic progenitors through activation of PKC signaling.
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Anti-TBK1 mouse monoclonal antibody [clone: 4E6]
Supplier: Cayman Chemical
Anti-TBK1 mouse monoclonal antibody [clone: 4E6]
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NETosis Assay Kit
Supplier: Cayman Chemical
For the measurement of NET-derived neutrophil elastase.
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Anti-NMDA Receptor NR2B Subunit Rabbit Polyclonal Antibody
Supplier: Cayman Chemical
Anti-NMDA Receptor NR2B Subunit Rabbit Polyclonal Antibody
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Anti-DNMT Mouse Monoclonal Antibody [clone: 60B1220.1]
Supplier: Cayman Chemical
Anti-DNMT Mouse Monoclonal Antibody [clone: 60B1220.1]
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Anti-MAPKK1 Rabbit Polyclonal Antibody
Supplier: Cayman Chemical
Anti-MAPKK1 Rabbit Polyclonal Antibody
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