"AAT Bioquest"

Supplier: AAT Bioquest

Our Buccutite™crosslinking technology provides the most convenient and effective crosslinking method to link two biomolecules with a high conjugation yield.

Supplier: AAT Bioquest

PD-10 Desalting columns contain sephadex G-25 resin for rapid buffer exchange, desalting, and removal of small contaminants (salts, dyes, radioactive labels) from samples using gravity flow or centrifugation.

Supplier: AAT Bioquest

Fluorescein-dT phosphoramidite provides a valuable tool to add the fluorescein tag to a desired location of an oligo sequence. For efficiently labeling an oligonucleotide.

Supplier: AAT Bioquest

AF532 PEG4 biotin conjugate contains Alexa Fluor 532 fluorophore that is well excited by the common 532 nm laser.

Supplier: AAT Bioquest

DY677 CEP (DyLight 677 phosphoramidite) is an excellent replacement to the commonly used Cy5.5 phosphoramidite.

Supplier: AAT Bioquest

VIC phosphoramidite is the most convenient building block to incorporate VIC tag into an oligonucleotide.

Supplier: AAT Bioquest

DiPO™-1 is the same compound to POPO®-1 (POPO® is the trademark of ThermoFisher).

Supplier: AAT Bioquest

A real-time polymerase chain reaction (real-time PCR), also known as quantitative polymerase chain reaction (qPCR), is a popular laboratory technique of molecular biology based on the polymerase chain reaction (PCR).

Supplier: AAT Bioquest

Prolite™ Orange is an alternative protein stain that can be used to replace SYPRO Orange Protein Gel Stain (SYPRO is the trademark of ThermoFisher).

Supplier: AAT Bioquest

Calcium measurement is critical for numerous biological investigations.

Supplier: AAT Bioquest

Adenosine triphosphate (ATP) plays a fundamental role in cellular energetics, metabolic regulation and cellular signaling.

Supplier: AAT Bioquest

Gentamicin is widely used for treating tuberculosis and Gram-negative infections and is particularly useful in neonatal intensive care units. Fluorophore-tagged drugs, such as gentamicin-Texas Red (GTTR) conjugates, have been used to identify drug trafficking routes across the BLB and into hair cells, and specifically in the cochlea - the sensory organ responsible for hearing. Identifying the mechanisms involved in the intracochlear trafficking of ototoxic drugs to hair cells is of fundamental as well as clinical importance. Texas Red-gentamicin conjugate (GTTR) provides researchers a valuable tool to study the cellular uptake, kinetics and distribution of gentamicin through fluorescence techniques, such as fluorescence microscopy, fluorescence correlation spectroscopy, single molecule spectroscopy. The TR fluorophore can be conveniently excited from 500-600 nm, with an emission maximum centered around 610 nm. Acute nephrotoxicity and permanent ototoxicity are serious side-effects that increase patient morbidity, or induce permanent auditory and vestibular deficits. Several approaches have been used to study the intracellular mechanisms induced by ototoxic drugs. However, ototoxic drugs must first cross the blood-labyrinth barrier (BLB) before entering sensory hair cells to exert their cytotoxic effect that leads to hearing loss and deafness. The BLB is similar to the blood-brain barrier (BBB), and is composed of tight junction-coupled endothelial and epithelial barrier layers that transport nutrients and ions from one side of the barrier to the other.

Supplier: AAT Bioquest

Biotin NTA (BNTA), a biotin-labeled nitrilotriacetic acid, is widely used to detect histidine-tagged proteins immobilized on nitrocellulose membranes with the detection limite of ~0.1 pmol.

Supplier: AAT Bioquest

Power Styramide™ Signal Amplification (PSA™) system is one of the most sensitive methods that can detect extremely low-abundance targets in cells and tissues with improved fluorescence signal 10 to 50 times higher than the widely used tyramide (TSA) reagents.

Supplier: AAT Bioquest

PD-10 Buffer Reservoir provides an easy and rapid way for equilibrating PD-10 columns.

Supplier: AAT Bioquest

DY647 CEP (DyLight 647 phosphoramidite) is an excellent replacement to the commonly used Cy5 phosphoramidite.