Differentiation and maturation kits for generation of motor neurons from human pluripotent stem cells.

Reduce the risk of culture failure by maturing and maintaining motor neuron cells using the STEMdiff™ Motor Neuron Maturation Kit. This kit combines neurophysiological BrainPhys™ Medium - proven to support long-term activity and maturation - with the supplements needed to produce functional motor neuron cultures. Cells matured with the STEMdiff™ Motor Neuron Maturation Kit exhibit high-level expression of expected motor neuron markers, including ChAT (>40%), across multiple cell lines. Use the resulting motor neuron cultures in a variety of applications, such as modeling human neurological disease or toxicity testing. The STEMdiff™ Motor Neuron Maturation Kit can also support co-culture with muscle cells generated using the MyoCult™ Differentiation Kit or with microglia generated using the STEMdiff™ Microglia Differentiation Kit.