Human Recombinant TNF-A (from E. coli)
Supplier: Shenandoah Biotechnology
About this item
Tumor necrosis factor alpha (TNF-α) is an inflammatory cytokine secreted by macrophages, monocytes, neutrophils, T cells, and NK-cells following stimulation by bacterial lipopolysaccharide (LPS).
- High quality
- Low endotoxin
- Affordable
TNF-α signal activation occurs through two receptors, TNFR1 and TNFR2. TNFR1 is expressed on most cell types, unlike TNFR2, which is expressed mainly on immune cells. TNF-α functions to stimulate phagocytosis in macrophages, chemoattract neutrophils, increase insulin resistance, and induce fever.
Delivery information: A certificate of analysis (COA) is supplied with each product shipped detailing purity, formulation, biological activity, endotoxin levels, reconstitution instructions and recommended storage conditions.
Caution: For research use only.
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Product Details & Documents
Tumor necrosis factor alpha (TNF-α) is an inflammatory cytokine secreted by macrophages, monocytes, neutrophils, T cells, and NK-cells following stimulation by bacterial lipopolysaccharide (LPS).
- High quality
- Low endotoxin
- Affordable
TNF-α signal activation occurs through two receptors, TNFR1 and TNFR2. TNFR1 is expressed on most cell types, unlike TNFR2, which is expressed mainly on immune cells. TNF-α functions to stimulate phagocytosis in macrophages, chemoattract neutrophils, increase insulin resistance, and induce fever.
Delivery information: A certificate of analysis (COA) is supplied with each product shipped detailing purity, formulation, biological activity, endotoxin levels, reconstitution instructions and recommended storage conditions.
Caution: For research use only.
Documents
Certificates
Search by Lot NumberLiterature reference - PubMed ID 24563081 Literature reference - PubMed ID 28637896
Additional Product Details
Specifications for Product Family
Specifications
Specifications
- Catalog No:
- SHBT100-111-10UG
- SHBT100-111-50UG
- SHBT100-111-100UG
- SHBT100-111-500UG
- SHBT100-111-1MG
- Protein/peptide name:
- TNF-alpha
- TNF-alpha
- TNF-alpha
- TNF-alpha
- TNF-alpha
- Protein synonyms:
- DIF|cachexin|cachectin|necrosin|TNFSF2|TNF|cytotoxin
- DIF|cachexin|cachectin|necrosin|TNFSF2|TNF|cytotoxin
- DIF|cachexin|cachectin|necrosin|TNFSF2|TNF|cytotoxin
- DIF|cachexin|cachectin|necrosin|TNFSF2|TNF|cytotoxin
- DIF|cachexin|cachectin|necrosin|TNFSF2|TNF|cytotoxin
- Protein/peptide type:
- Recombinant
- Recombinant
- Recombinant
- Recombinant
- Recombinant
- Protein function:
- Cytokine
- Cytokine
- Cytokine
- Cytokine
- Cytokine
- Species:
- Human
- Human
- Human
- Human
- Human
- Kilde:
- E. coli
- E. coli
- E. coli
- E. coli
- E. coli
- Konjugation:
- Unconjugated
- Unconjugated
- Unconjugated
- Unconjugated
- Unconjugated
- Gen ID:
- P01375
- P01375
- P01375
- P01375
- P01375
- Sekvens:
- MVRSSSRTPS DKPVAHVVAN PQAEGQLQWL NRRANALLAN GVELRDNQLV VPSEGLYLIY SQVLFKGQGC PSTHVLLTHT ISRIAVSYQT KVNLLSAIKS PCQRETPEGA EAKPWYEPIY LGGVFQLEKG DRLSAEINRP DYLDFAESGQ VYFGIIAL
- MVRSSSRTPS DKPVAHVVAN PQAEGQLQWL NRRANALLAN GVELRDNQLV VPSEGLYLIY SQVLFKGQGC PSTHVLLTHT ISRIAVSYQT KVNLLSAIKS PCQRETPEGA EAKPWYEPIY LGGVFQLEKG DRLSAEINRP DYLDFAESGQ VYFGIIAL
- MVRSSSRTPS DKPVAHVVAN PQAEGQLQWL NRRANALLAN GVELRDNQLV VPSEGLYLIY SQVLFKGQGC PSTHVLLTHT ISRIAVSYQT KVNLLSAIKS PCQRETPEGA EAKPWYEPIY LGGVFQLEKG DRLSAEINRP DYLDFAESGQ VYFGIIAL
- MVRSSSRTPS DKPVAHVVAN PQAEGQLQWL NRRANALLAN GVELRDNQLV VPSEGLYLIY SQVLFKGQGC PSTHVLLTHT ISRIAVSYQT KVNLLSAIKS PCQRETPEGA EAKPWYEPIY LGGVFQLEKG DRLSAEINRP DYLDFAESGQ VYFGIIAL
- MVRSSSRTPS DKPVAHVVAN PQAEGQLQWL NRRANALLAN GVELRDNQLV VPSEGLYLIY SQVLFKGQGC PSTHVLLTHT ISRIAVSYQT KVNLLSAIKS PCQRETPEGA EAKPWYEPIY LGGVFQLEKG DRLSAEINRP DYLDFAESGQ VYFGIIAL
- Protease-free:
- N
- N
- N
- N
- N
- Dyrefri:
- N
- N
- N
- N
- N
- Fri for nukleaser:
- N
- N
- N
- N
- N
- Bærerfri:
- Y
- Y
- Y
- Y
- Y
- Endotoxin-free:
- N
- N
- N
- N
- N
- Endotoksin niveau:
- Low
- Low
- Low
- Low
- Low
- Endotoksinindhold:
- Endotoxin LAL (EU/µg) ≤1
- Endotoxin LAL (EU/µg) ≤1
- Endotoxin LAL (EU/µg) ≤1
- Endotoxin LAL (EU/µg) ≤1
- Endotoxin LAL (EU/µg) ≤1
- UniProtKB:
- P01375
- P01375
- P01375
- P01375
- P01375
- Biologisk aktivitet:
- Bioactivity assay: Cytolysis of mouse L929 cells in the presence of actinomycin D, ED50 ≤2 ng/ml, bioactivity ≥5,0×10⁵ units/mg
- Bioactivity assay: Cytolysis of mouse L929 cells in the presence of actinomycin D, ED50 ≤2 ng/ml, bioactivity ≥5,0×10⁵ units/mg
- Bioactivity assay: Cytolysis of mouse L929 cells in the presence of actinomycin D, ED50 ≤2 ng/ml, bioactivity ≥5,0×10⁵ units/mg
- Bioactivity assay: Cytolysis of mouse L929 cells in the presence of actinomycin D, ED50 ≤2 ng/ml, bioactivity ≥5,0×10⁵ units/mg
- Bioactivity assay: Cytolysis of mouse L929 cells in the presence of actinomycin D, ED50 ≤2 ng/ml, bioactivity ≥5,0×10⁵ units/mg
- Renhed:
- ≥95%
- ≥95%
- ≥95%
- ≥95%
- ≥95%
- Kvalitet:
- RUO
- RUO
- RUO
- RUO
- RUO
- Formulering:
- 10 mM sodium phosphate, pH 7,5
- 10 mM sodium phosphate, pH 7,5
- 10 mM sodium phosphate, pH 7,5
- 10 mM sodium phosphate, pH 7,5
- 10 mM sodium phosphate, pH 7,5
- Molekylvægt:
- 17,5 kDa
- 17,5 kDa
- 17,5 kDa
- 17,5 kDa
- 17,5 kDa
- Reconstitution instructions:
- Sterile water at 0,1 mg/ml
- Sterile water at 0,1 mg/ml
- Sterile water at 0,1 mg/ml
- Sterile water at 0,1 mg/ml
- Sterile water at 0,1 mg/ml
- Opbevaring betingelser:
- −20 °C
- −20 °C
- −20 °C
- −20 °C
- −20 °C
- Shipping temperature:
- Room temperature
- Room temperature
- Room temperature
- Room temperature
- Room temperature
- Tested applications:
- Bioassay
- Bioassay
- Bioassay
- Bioassay
- Bioassay
Specifications
Product Family Options
Product Information
- PakningPaknAvailabilityPrice
- Specifications:
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Specifications
Cat. No.SHBT100-111-10UGProtein/peptide nameTNF-alphaProtein synonymsDIF|cachexin|cachectin|necrosin|TNFSF2|TNF|cytotoxinProtein/peptide typeRecombinantProtein functionCytokineSpeciesHumanKildeE. coliKonjugationUnconjugatedGen IDP01375SekvensMVRSSSRTPS DKPVAHVVAN PQAEGQLQWL NRRANALLAN GVELRDNQLV VPSEGLYLIY SQVLFKGQGC PSTHVLLTHT ISRIAVSYQT KVNLLSAIKS PCQRETPEGA EAKPWYEPIY LGGVFQLEKG DRLSAEINRP DYLDFAESGQ VYFGIIALProtease-freeNDyrefriNFri for nukleaserNBærerfriYEndotoxin-freeNEndotoksin niveauLowEndotoksinindholdEndotoxin LAL (EU/µg) ≤1UniProtKBP01375Biologisk aktivitetBioactivity assay: Cytolysis of mouse L929 cells in the presence of actinomycin D, ED50 ≤2 ng/ml, bioactivity ≥5,0×10⁵ units/mgRenhed≥95%KvalitetRUOFormulering10 mM sodium phosphate, pH 7,5Molekylvægt17,5 kDaReconstitution instructionsSterile water at 0,1 mg/mlOpbevaring betingelser−20 °CShipping temperatureRoom temperatureTested applicationsBioassay - Specifications:
More
Specifications
Cat. No.SHBT100-111-50UGProtein/peptide nameTNF-alphaProtein synonymsDIF|cachexin|cachectin|necrosin|TNFSF2|TNF|cytotoxinProtein/peptide typeRecombinantProtein functionCytokineSpeciesHumanKildeE. coliKonjugationUnconjugatedGen IDP01375SekvensMVRSSSRTPS DKPVAHVVAN PQAEGQLQWL NRRANALLAN GVELRDNQLV VPSEGLYLIY SQVLFKGQGC PSTHVLLTHT ISRIAVSYQT KVNLLSAIKS PCQRETPEGA EAKPWYEPIY LGGVFQLEKG DRLSAEINRP DYLDFAESGQ VYFGIIALProtease-freeNDyrefriNFri for nukleaserNBærerfriYEndotoxin-freeNEndotoksin niveauLowEndotoksinindholdEndotoxin LAL (EU/µg) ≤1UniProtKBP01375Biologisk aktivitetBioactivity assay: Cytolysis of mouse L929 cells in the presence of actinomycin D, ED50 ≤2 ng/ml, bioactivity ≥5,0×10⁵ units/mgRenhed≥95%KvalitetRUOFormulering10 mM sodium phosphate, pH 7,5Molekylvægt17,5 kDaReconstitution instructionsSterile water at 0,1 mg/mlOpbevaring betingelser−20 °CShipping temperatureRoom temperatureTested applicationsBioassay - Specifications:
More
Specifications
Cat. No.SHBT100-111-100UGProtein/peptide nameTNF-alphaProtein synonymsDIF|cachexin|cachectin|necrosin|TNFSF2|TNF|cytotoxinProtein/peptide typeRecombinantProtein functionCytokineSpeciesHumanKildeE. coliKonjugationUnconjugatedGen IDP01375SekvensMVRSSSRTPS DKPVAHVVAN PQAEGQLQWL NRRANALLAN GVELRDNQLV VPSEGLYLIY SQVLFKGQGC PSTHVLLTHT ISRIAVSYQT KVNLLSAIKS PCQRETPEGA EAKPWYEPIY LGGVFQLEKG DRLSAEINRP DYLDFAESGQ VYFGIIALProtease-freeNDyrefriNFri for nukleaserNBærerfriYEndotoxin-freeNEndotoksin niveauLowEndotoksinindholdEndotoxin LAL (EU/µg) ≤1UniProtKBP01375Biologisk aktivitetBioactivity assay: Cytolysis of mouse L929 cells in the presence of actinomycin D, ED50 ≤2 ng/ml, bioactivity ≥5,0×10⁵ units/mgRenhed≥95%KvalitetRUOFormulering10 mM sodium phosphate, pH 7,5Molekylvægt17,5 kDaReconstitution instructionsSterile water at 0,1 mg/mlOpbevaring betingelser−20 °CShipping temperatureRoom temperatureTested applicationsBioassay - Specifications:
More
Specifications
Cat. No.SHBT100-111-500UGProtein/peptide nameTNF-alphaProtein synonymsDIF|cachexin|cachectin|necrosin|TNFSF2|TNF|cytotoxinProtein/peptide typeRecombinantProtein functionCytokineSpeciesHumanKildeE. coliKonjugationUnconjugatedGen IDP01375SekvensMVRSSSRTPS DKPVAHVVAN PQAEGQLQWL NRRANALLAN GVELRDNQLV VPSEGLYLIY SQVLFKGQGC PSTHVLLTHT ISRIAVSYQT KVNLLSAIKS PCQRETPEGA EAKPWYEPIY LGGVFQLEKG DRLSAEINRP DYLDFAESGQ VYFGIIALProtease-freeNDyrefriNFri for nukleaserNBærerfriYEndotoxin-freeNEndotoksin niveauLowEndotoksinindholdEndotoxin LAL (EU/µg) ≤1UniProtKBP01375Biologisk aktivitetBioactivity assay: Cytolysis of mouse L929 cells in the presence of actinomycin D, ED50 ≤2 ng/ml, bioactivity ≥5,0×10⁵ units/mgRenhed≥95%KvalitetRUOFormulering10 mM sodium phosphate, pH 7,5Molekylvægt17,5 kDaReconstitution instructionsSterile water at 0,1 mg/mlOpbevaring betingelser−20 °CShipping temperatureRoom temperatureTested applicationsBioassay - Specifications:
More
Specifications
Cat. No.SHBT100-111-1MGProtein/peptide nameTNF-alphaProtein synonymsDIF|cachexin|cachectin|necrosin|TNFSF2|TNF|cytotoxinProtein/peptide typeRecombinantProtein functionCytokineSpeciesHumanKildeE. coliKonjugationUnconjugatedGen IDP01375SekvensMVRSSSRTPS DKPVAHVVAN PQAEGQLQWL NRRANALLAN GVELRDNQLV VPSEGLYLIY SQVLFKGQGC PSTHVLLTHT ISRIAVSYQT KVNLLSAIKS PCQRETPEGA EAKPWYEPIY LGGVFQLEKG DRLSAEINRP DYLDFAESGQ VYFGIIALProtease-freeNDyrefriNFri for nukleaserNBærerfriYEndotoxin-freeNEndotoksin niveauLowEndotoksinindholdEndotoxin LAL (EU/µg) ≤1UniProtKBP01375Biologisk aktivitetBioactivity assay: Cytolysis of mouse L929 cells in the presence of actinomycin D, ED50 ≤2 ng/ml, bioactivity ≥5,0×10⁵ units/mgRenhed≥95%KvalitetRUOFormulering10 mM sodium phosphate, pH 7,5Molekylvægt17,5 kDaReconstitution instructionsSterile water at 0,1 mg/mlOpbevaring betingelser−20 °CShipping temperatureRoom temperatureTested applicationsBioassay
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