Polyclonal antibody for CD146/MCAM detection. Host: Rabbit.Size: 100μg/vial. Tested applications: IHC-P. Reactive species: Human. CD146/MCAM information: Molecular Weight: 71607 MW; Subcellular Localization: Membrane; Single-pass type I membrane protein; Tissue Specificity: Detected in endothelial cells in vascular tissue throughout the body. May appear at the surface of neural crest cells during their embryonic migration. Appears to be limited to vascular smooth muscle in normal adult tissues. Associated with tumor progression and the development of metastasis in human malignant melanoma. Expressed most strongly on metastatic lesions and advanced primary tumors and is only rarely detected in benign melanocytic nevi and thin primary melanomas with a low probability of metastasis.

Type: Primary
Antigen: CD146
Clonality: Polyclonal
Clone:
Conjugation:
Epitope:
Host:
Isotype: Rabbit
Reactivity: Human