Human recombinant IL4 (from E. coli)
Product Details & Documents
Interleukin-4 (IL-4) is a pleiotropic cytokine that regulates diverse T and B cell responses including cell proliferation, survival and gene expression. IL-4 is produced by mast cells, T cells, and bone marrow stromal cells. IL-4 regulates the differentiation of naive CD4+ T cells into helper Th2 cells, characterized by their cytokine-secretion profile that includes secretion of IL-4, IL-5, IL-6, IL-10, and IL-13, which favor a humoral immune response. Another dominant function of IL-4 is the regulation of immunoglobulin class switching to the IgG1 and IgE isotypes. Excessive IL-4 production by Th2 cells has been associated with elevated IgE production and allergic response.
- This recombinant protein can be used for biological assays. For research use only.
Documents
75788-804.pdf
Datablad
Specifikationer
Specifikationer
- Pakn:50 µG
- Protein/peptide name:IL4
- Protein synonyms:IL4|Lymphocyte Stimulatory Factor 1|IL-4|Binetrakin|Pitrakinra|B-Cell Stimulatory Factor 1|BSF-1|Interleukin-4
- Biologisk aktivitet:ED50 is less than 2 ng/ml as determined by the dose-dependent stimulation of TF-1 cells.<br />Specific Activity of 5.0 x 10<sup>6</sup> IU/mg.
- Cat. No.:PRSI91-040
- Protein/peptide type:Recombinant
- Sekvens:His25-Ser153
- Molekylvægt:15.1 kD
- Formulering:Lyophilized from a 0.2 um filtered solution of 20mM PB, 150mM NaCl, pH 7.4. Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 ug/ml. Dissolve the Lyophilized protein in ddH2O. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
- Renhed:> 95% as determined by reducing SDS-PAGE
- Tested applications:Bioassay
- Kilde:E. coli
- Species:Human
- Opbevaring betingelser:Lyophilized protein should be stored at −20 °C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7 °C for 2-7 days. Aliquots of reconstituted samples are stable at −20 °C for 3 months.
Specifikationer
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