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Human recombinant IL4 (from <i>E. coli</i>)

Human recombinant IL4 (from E. coli)

50 µG
Katalog # PRSI91-040
Leverandør:   ProSci Inc.
Human recombinant IL4 (from <i>E. coli</i>)
Katalog # PRSI91-040
Leverandør:  ProSci Inc.
CAS nummer:  
Human recombinant IL4 (from E. coli)

50 µG

CAS nummer:  
Price
4.500,00 kr
Log ind for tilgængelighed
1 * 1 Each
Product Details & Documents

Interleukin-4 (IL-4) is a pleiotropic cytokine that regulates diverse T and B cell responses including cell proliferation, survival and gene expression. IL-4 is produced by mast cells, T cells, and bone marrow stromal cells. IL-4 regulates the differentiation of naive CD4+ T cells into helper Th2 cells, characterized by their cytokine-secretion profile that includes secretion of IL-4, IL-5, IL-6, IL-10, and IL-13, which favor a humoral immune response. Another dominant function of IL-4 is the regulation of immunoglobulin class switching to the IgG1 and IgE isotypes. Excessive IL-4 production by Th2 cells has been associated with elevated IgE production and allergic response.

  • This recombinant protein can be used for biological assays. For research use only.

Documents

Specifikationer

Specifikationer

  • Pakn:
    50 µG
  • Protein/peptide name:
    IL4
  • Protein synonyms:
    IL4|Lymphocyte Stimulatory Factor 1|IL-4|Binetrakin|Pitrakinra|B-Cell Stimulatory Factor 1|BSF-1|Interleukin-4
  • Biologisk aktivitet:
    ED50 is less than 2 ng/ml as determined by the dose-dependent stimulation of TF-1 cells.<br />Specific Activity of 5.0 x 10<sup>6</sup> IU/mg.
  • Cat. No.:
    PRSI91-040
  • Protein/peptide type:
    Recombinant
  • Sekvens:
    His25-Ser153
  • Molekylvægt:
    15.1 kD
  • Formulering:
    Lyophilized from a 0.2 um filtered solution of 20mM PB, 150mM NaCl, pH 7.4. Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 ug/ml. Dissolve the Lyophilized protein in ddH2O. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
  • Renhed:
    > 95% as determined by reducing SDS-PAGE
  • Tested applications:
    Bioassay
  • Kilde:
    E. coli
  • Species:
    Human
  • Opbevaring betingelser:
    Lyophilized protein should be stored at −20 °C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7 °C for 2-7 days. Aliquots of reconstituted samples are stable at −20 °C for 3 months.

Specifikationer

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