PP242

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PP242 free base ≥99%

Supplier: Apollo Scientific

PP242 free base ≥99%

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PP242

Supplier: Abcam

Potent, selective and ATP-competitive mTOR inhibitor (IC₅₀ =8 nM). Inhibits both mTORC1 and mTORC2. Activates ERK via TORC1/eIF-4E/RAF pathway in cancer cells. Selective for mTOR over PI3K family kinases (IC₅₀ values are 0,1 (p110γ), 0,41 (DNA-PK), 1,27 (p110δ), 1,96 (p110α) and 2,2 (p110β) μM). Anticancer agent. Active in vivoand in vitro.

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Torkinib

Supplier: Apollo Scientific

Torkinib

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