937 Results for: "single-use assemblies"

Supplier: ProSci Inc.

The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. PSMA2 is a member of the peptidase T1A family, that is a 20S core alpha subunit.The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the peptidase T1A family, that is a 20S core alpha subunit. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

Supplier: Merck Millipore (Novagen)

The NovaTaq PCR Master Mix is a ready to use 2X concentrated mixture of NovaTaq DNA polymerase, ultra-pure deoxynucleotides, and reaction buffer without magnesium chloride. The master mix simplifies the assembly of PCR reactions and offers advantages of times savings, consistency, and minimal risk of contamination. Simply add the NovaTaq PCR master mix to an equal volume containing the required amount of magnesium chloride, DNA template, and primers, and the reaction is ready for thermal cycling. The final diluted reaction contains 2,5 units of NovaTaq DNA polymerase per 100 µl. Sufficient components are included for 200 standard 50 µl (or 100×100 µl) amplification reactions.

Supplier: ProSci Inc.

CHRNA4 is a nicotinic acetylcholine receptor, which belongs to a superfamily of ligand-gated ion channels that play a role in fast signal transmission at synapses. These pentameric receptors can bind acetylcholine, which causes an extensive change in conformation that leads to the opening of an ion-conducting channel across the plasma membrane. This protein is an integral membrane receptor subunit that can interact with either nAChR beta-2 or nAChR beta-4 to form a functional receptor. Mutations in this gene cause nocturnal frontal lobe epilepsy type 1. Polymorphisms in this gene that provide protection against nicotine addiction have been described. This gene encodes a nicotinic acetylcholine receptor, which belongs to a superfamily of ligand-gated ion channels that play a role in fast signal transmission at synapses. These pentameric receptors can bind acetylcholine, which causes an extensive change in conformation that leads to the opening of an ion-conducting channel across the plasma membrane. This protein is an integral membrane receptor subunit that can interact with either nAChR beta-2 or nAChR beta-4 to form a functional receptor. Mutations in this gene cause nocturnal frontal lobe epilepsy type 1. Polymorphisms in this gene that provide protection against nicotine addiction have been described. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

Supplier: ProSci Inc.

CYP1A1 is a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by some polycyclic aromatic hydrocarbons (PAHs), some of which are found in cigarette smoke. The enzyme's endogenous substrate is unknown; however, it is able to metabolize some PAHs to carcinogenic intermediates. CYP1A1 has been associated with lung cancer risk. This gene, CYP1A1, encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by some polycyclic aromatic hydrocarbons (PAHs), some of which are found in cigarette smoke. The enzyme's endogenous substrate is unknown; however, it is able to metabolize some PAHs to carcinogenic intermediates. The gene has been associated with lung cancer risk. A related family member, CYP1A2, is located approximately 25 kb away from CYP1A1 on chromosome 15. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

Supplier: ProSci Inc.

CYP1A1 is a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by some polycyclic aromatic hydrocarbons (PAHs), some of which are found in cigarette smoke. The enzyme's endogenous substrate is unknown; however, it is able to metabolize some PAHs to carcinogenic intermediates. CYP1A1 has been associated with lung cancer risk. This gene, CYP1A1, encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by some polycyclic aromatic hydrocarbons (PAHs), some of which are found in cigarette smoke. The enzyme's endogenous substrate is unknown; however, it is able to metabolize some PAHs to carcinogenic intermediates. The gene has been associated with lung cancer risk. A related family member, CYP1A2, is located approximately 25 kb away from CYP1A1 on chromosome 15. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

Supplier: ProSci Inc.

The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. RBMXL2 has two RRM domains that bind RNAs. RBMXL2 has similarity to HNRPG and RBMY proteins and it is suggested to replace HNRPG protein function during meiotic prophase or act as a germ cell-specific splicing regulator. It primarily localizes to the nuclei of meiotic spermatocytes. This gene is a candidate for autosomal male infertility.This gene belongs to the HNRPG subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene has two RRM domains that bind RNAs. This gene is intronless and is thought to be derived from a processed retroposon. However, unlike many retroposon-derived genes, this gene is not a pseudogene. The encoded protein has similarity to HNRPG and RBMY proteins and it is suggested to replace HNRPG protein function during meiotic prophase or act as a germ cell-specific splicing regulator. It primarily localizes to the nuclei of meiotic spermatocytes. This gene is a candidate for autosomal male infertility. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. PRIMARYREFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-2215 AC100875.3 67063-69277 c

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Guanine nucleotide-binding proteins (G proteins) form a large family of signal-transducing molecules. They are found as heterotrimers made up of alpha, beta, and gamma subunits. Members of the G protein family have been characterized most extensively on the basis of the alpha subunit, which binds guanine nucleotide, is capable of hydrolyzing GTP, and interacts with specific receptor and effector molecules. The G protein family includes Gs and Gi, the stimulatory and inhibitory GTP-binding regulators of adenylate cyclase; Go, a protein abundant in brain (GNAO1); and transducin-1 (GNAT1) and transducin-2 (GNAT2), proteins involved in phototransduction in retinal rods and cones, respectively.Guanine nucleotide-binding proteins (G proteins) form a large family of signal-transducing molecules. They are found as heterotrimers made up of alpha, beta, and gamma subunits. Members of the G protein family have been characterized most extensively on the basis of the alpha subunit, which binds guanine nucleotide, is capable of hydrolyzing GTP, and interacts with specific receptor and effector molecules. The G protein family includes Gs (MIM 139320) and Gi, the stimulatory and inhibitory GTP-binding regulators of adenylate cyclase; Go, a protein abundant in brain (GNAO1; MIM 139311); and transducin-1 (GNAT1; MIM 139330) and transducin-2 (GNAT2; MIM 139340), proteins involved in phototransduction in retinal rods and cones, respectively (Sullivan et al., 1986 [PubMed 3092218]; Bray et al., 1987 [PubMed 3110783]). Suki et al. (1987) [PubMed 2440724] concluded that the human genome contains at least 3 nonallelic genes for alpha-i-type subunits of G protein; see, e.g, GNAI2 (MIM 139360), GNAI3 (MIM 139370), and GNAIH (MIM 139180).[supplied by OMIM]. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

Supplier: VWR Collection

A unique design of rotator makes this unit suitable for a wide range of mixing applications in biochemistry, molecular biology and histochemistry. The rotisserie assemblies allow for mixing tubes vertically, horizontally, or any position in between, therefore, gentle mixing, using a horizontal position is easily accommodated for applications such as hybridisation. Alternatively rotation with vertically positioned tubes produces a tumbling motion suitable for mixing samples in blood tubes. The two halves of the rotisserie can be adjusted independently of each other to increase versatility and facilitate optimisation of mixing.

Supplier: LABCONCO

Single Hexagonal Rotor (For 90 ea. 1.5 ml microcentrifuge tubes) 1 * 1 items

Supplier: Corning

Center cap assembly, for glass spinner flask with 70 mm center neck using impeller assembly with 1/4 OD shaft 1 * 1 items

Supplier: G-Biosciences

A C1orf31 (Cytochrome c oxidase assembly factor 6 homolog) ELISA with a senstivity of 0.188ng/ml and a range of 0.313-20ng/ml. Uses the detection method Sandwich ELISA, Double Antibody 1 * 1 KIT

Supplier: 3M

3M Reusable Respirator Head Harness Assembly Designed for use with 3M™ Half Facepiece 6000 Series (sold separately) 1 * 1 items

Supplier: NEXOPART

Power contactor for eControl Lite (foreign vacuum cleaner) Vacuum cleaner with the following power specifications can be used: V 100 230 400 kW max 0,9 2,2 4(le=9A) Plug and socket must be provided and assembled by the customer. 1 * 1 items

Supplier: G-Biosciences

G-CAPSULE is a single use electroelution device for rapid recovery of proteins and nucleic acids from electrophoresis gel. Isolates 20bp of DNA or RNA or protein 4kDa in 60 seconds. Simply pick up the protein band with the Gel-Pick, assemble with Gen 1 * 55 items

Supplier: IBS Stock Items

PETG Vented with Tubing Gamma irradiated ,10 per case 1 * 10 items

Supplier: IBS Stock Items

PETG Vented with Tubing Gamma irradiated ,10 per case 1 * 10 items

Supplier: IBS Stock Items

PETG Vented with Tubing Gamma irradiated ,10 per case 1 * 10 items

Supplier: Thermo Fisher Scientific

Inoculator assembly disposable with single inoculum tray 1 * 50 items

Supplier: Merck

SQ SINGLE HOUSING WALL BRACKET ASSEMBLY 1 * 1 items

Supplier: Agilent

DLW-2 loop assembly, used with 1290 Infinity liquid chromatography series autosamplers, models G4278A and G4277A 1 * 1 items

Supplier: Agilent

Injector assembly for gc-icp-ms. suits gc-icp-ms interface used with icp-ms 1 * 1 items

Supplier: Agilent

Ceramic source board and cable assembly, used with series 5975 and 5977 gas chromatography/mass spectrometry systems 1 * 1 items

Supplier: TIGER-VAC

EPDM SUCTION HOSE ASSEMBLY SD*, Ø1.5 (38mm) x 10'(3m), FOR USE WITH 2 (50mm) CAMLOCK SUCTION INTAKE 1 * 1 items

Supplier: WARING BLENDOR

2.0 Litre Stainless Steel Container Complete with Blade Assembly & Lid (for use on MX blenders) 1 * 1 items

Supplier: RPB SAFETY

RPB Flow Control Device Assembly and belt. For use with RPB’s range of SAR respiratory head top, inc. Z-Link and T-Link null

Supplier: PerkinElmer

CONSUMABLE SCREEN FOR USE ON THE DIRECT SAMPLE ANALYSIS (DSA) ION SOURCE FOR AXION 2 TOF MS. FOR HOLDING LIQUID SAMPLES. USE WITH DS A MESH HOLDER ASSEMBLY (MZ300579). 1 * 1 items

Supplier: TIGER-VAC

EPDM SUCTION HOSE ASSEMBLY, SD*, Ø1.5 (38mm) x 10'(3m), w/SS FEMALE CAMLOCK <(>&<)> S/S FEMALE SCREW TYPE FOR USE WITH 1.5 (38mm) CAMLOCK SUCTION INLET 1 * 1 items

Supplier: Hach

Vacuum filter microfunnel assembly, pk/50, Sterile disposable funnel with petri dish, pad, and 0.45 um white gridded membrane filter , use with 2831600 1 * 50 items

Supplier: PerkinElmer

NOTE: THIS FILTER KIT IS NOT FOR USE WITH OXYGEN. COMPATIBLE WITH ICP-MS INSTRUMENTS SUCH AS THE NEXION 1000/2000/350/300. 1 * 1 items

Supplier: PerkinElmer

END CAP FOR THE PINAACLE HIGH SENSITIVITY NEBULIZER ASSEMBLY (N3160144) FOR USE WITH PINAACLE 900 ATOMIC ABSORPTION SPECTROMETERS. 1 * 1 items