837 Results for: "Sulfuric Acid"

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Anti-NDUFS7 Rabbit Polyclonal Antibody (Alexa Fluor® 350)

Supplier: Bioss

Located in the mitochondrial inner membrane, mitochondrial complex I is the first and largest enzyme in the electron transport chain of oxidative phosphorylation. By oxidizing NADH that is produced in the Krebs cycle, this complex utilizes the two electrons to reduce ubiquinone to ubiquinol, thereby initiating the passage of electrons to successive complexes and ultimately leading to the reduction of oxygen to water. Mitochondrial complex I consists of over 40 subunits and is of considerable clinical interest since defects in any of the subunits can lead to various myopathies and neuropathies. As a subunit of mitochondrial complex I, NDUFS7 (NADH dehydrogenase [ubiquinone] iron-sulfur protein 7), also designated NADH-ubiquinone oxidoreductase 20 kDa subunit, is a 213 amino acid protein that is suggested to be required for catalytic activity. Defects in the gene encoding NDUFS7 are the cause of Leigh syndrome, a severe neurological disorder that is characterized by bilaterally symmetrical necrotic lesions in subcortical brain regions.

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Lithium hydroxide monohydrate ≥99.9% (trace metals basis) battery grade

Supplier: Merck

Lithium hydroxide monohydrate is a white-to-colourless, crystalline salt. The monohydrate is hygroscopic. It is soluble in water and generates heat when dissolving. It is also soluble in methanol, somewhat soluble in ethanol, but only sparingly soluble in isopropanol. Lithium hydroxide is produced in several ways. Most commonly, lithium carbonate is reacted with calcium hydroxide in a metathesis reaction. This directly yields lithium hydroxide hydrate, which is separated from the insoluble calcium carbonate byproduct and purified. Alternatively, when the source of lithium is spodumene ore, the ore can be converted to lithium hydroxide without first forming the carbonate. In the process, the lithium ore is treated with high-temperatures and sulfuric acid to form lithium sulfate; then the lithium sulfate is reacted with sodium hydroxide to form lithium hydroxide hydrate, which is purified.

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Gentamicin sulphate

Supplier: MP Biomedicals

Gentamicin is an aminoglycoside antibiotic complex produced by fermentation of Micromonospora purpurea or M. echinospora. It is a mixture of 3 major components designated as C1, C1a, and C2. Gentamicin is used as the sulfate salt. Each component consists of five basic nitrogens and requires five equivalents of sulfuric acid per mole of gentamicin base. Mode of action: Gentamicin causes codon misreading by binding to the 30S ribosomal subunit, blocking the translocation of peptidyl-tRNA from the acceptor site to the donor site.The bactericidal effect of gentamicin on Pseudomonas aeruginosa is exerted by the binding of gentamicin to the outer membrane, where it displaces natural cations, destabilizes the membrane, and forms holes in the cell surface.Antimicrobial spectrum: Gram-negative bacteria, Staphylococcus aureus and other Gram-positive bacteria. Gentamicin sulfate is a broad spectrum antibiotic. It inhibits the growth of a wide variety of Gram-positive and Gram-negative microorganisms, including strains resistant to tetracycline, chloramphenicol, kanamycin, and colistin, particularly strains of Pseudomonas, Proteus, Staphylococcus, and Streptococcus. Gentamicin sulfate inhibits bacterial protein biosynthesis by binding to the 30S subunit of the ribosome.