"Stemcell Technologies"

Supplier: Stemcell Technologies

Immunomagnetic positive selection of particle-free human cells labelled with PE-conjugated antibodies.

Supplier: Stemcell Technologies

Rat monoclonal antibody against mouse CD3, FITC-conjugated.

Supplier: Stemcell Technologies

Mouse monoclonal IgG2b antibody against human CD68, APC-conjugated.

Supplier: Stemcell Technologies

Rabbit monoclonal antibody against human, mouse, rat SOX2 (ANOP3).

Supplier: Stemcell Technologies

RANTES (regulated upon activation, normal T cell expressed and secreted), also known as CCL5, is a member of the CC family of chemokines and is able to recruit leukocytes to sites of inflammation (Schall et al.). RANTES is secreted by T lymphocytes, macrophages, platelets, synovial fibroblasts, tubular epithelium, and certain types of tumor cells (Aldinucci and Colombatti; Soria and Ben-Baruch). This chemokine exerts its effect by interacting with the chemokine receptors CCR1, CCR3, CCR4, and CCR5. RANTES plays an active role in recruiting a variety of leukocytes into inflammatory sites, including T cells, macrophages, eosinophils, and basophils. In collaboration with certain cytokines that are released by T cells such as IL-2 and IFN-γ, RANTES also induces the activation and proliferation of NK cells to generate CC chemokine-activated killer cells, which are highly cytolytic (Lv et al.; Maghazachi et al.). It has been shown that RANTES produced by CD8+ T cells inhibits HIV infection of primary human peripheral blood mononuclear cells (Appay and Rowland-Jones; Cocchi et al.).

Supplier: Stemcell Technologies

Mouse monoclonal IgG1 antibody against human, rhesus, cynomolgus CD11b, PE-conjugated.

Supplier: Stemcell Technologies

Mouse monoclonal IgG1 antibody against human, mouse, rat acetylated alpha-tubulin (acetyl K40).

Supplier: Stemcell Technologies

Immunomagnetic positive selection of human CD33+ cells (e.g. myeloid cells).

Supplier: Stemcell Technologies

Human Recombinant Angiotensin-Converting Enzyme 2 (ACE2) Protein, aa18-740, is expressed in HEK293 cells. ACE2 activity results in vasodilation by degrading vasoconstrictor angiotensin II to produce vasodilator angiotensin. Decreased expression of this enzyme is associated with cardiovascular disease and possibly also glomerular injury in diabetic nephropathy. ACE2 contains a peptidase domain at the N-terminus and a single transmembrane helix. ACE2 is also the primary human receptor for the surface spike glycoprotein of SARS-CoV-2 and SARS-CoV. This receptor is expressed in human lung and small intestine epithelia as well as the heart, kidney, and testes. The peptidase domain of ACE2 binds to the protein-binding domain of the S1 protein subunit of the spike protein; this binding results in a cleavage site becoming exposed. Cleavage, or ‘protein priming’, is done by TMPRSS2, a cellular serine protease, and by cathepsins. This cleavage activates the S2 subunit of the spike protein, allowing the fusion of the viral membrane to the host cell membrane. At the carboxy terminus, Human Recombinant ACE2 Protein contains a TEV site and a human IgG1 Fc tag.

Supplier: Stemcell Technologies

Mouse monoclonal IgG3, kappa isotype control antibody, PE-conjugated.

Supplier: Stemcell Technologies

Hanks’ Balanced Salt Solution (HBSS) can be used for diluting, washing, irrigating or as a transporting solution for cell or tissue culture. It provides a buffering system to maintain the physiological pH range and osmotic balance of culture media, and provides cells with a source of water and essential inorganic ions and a carbohydrate as an energy source. Selection of suitable nutrient medium is dependent on type of cell, culture conditions, and degree of chemical definition required for the cell culture application.

Supplier: Stemcell Technologies

qPCR analysis kit for detecting the majority of karyotypic abnormalities reported in human ES and iPS cells.

Supplier: Stemcell Technologies

Mouse monoclonal IgG2a, kappa isotype control antibody, FITC-conjugated.

Supplier: Stemcell Technologies

Culture medium for long-term expansion and maintenance of human liver organoids.

Supplier: Stemcell Technologies

Mouse monoclonal IgG2a antibody against human, mouse, rat beta-tubulin III, unconjugated.

Supplier: Stemcell Technologies

Rat monoclonal IgG2b antibody against mouse CD25, FITC-conjugated.