2779 Results for: "STEMCELL Technologies"

Supplier: STEMCELL Technologies

Membrane-permeable fluorescent probe for the detection of live neurons - 0,1 ml.

Supplier: STEMCELL Technologies

Mouse monoclonal IgG1 antibody against human, rhesus, cynomolgus CD83, Alexa Fluor® 488-conjugated.

Supplier: STEMCELL Technologies

Mouse monoclonal IgG2b antibody against human, rhesus HLA-DR, Alexa Fluor® 488-conjugated.

Supplier: STEMCELL Technologies

Mouse monoclonal IgG1 antibody against human, chimpanzee CD22, PE­conjugated.

Supplier: STEMCELL Technologies

Rat monoclonal IgG2a antibody against mouse CD4, unconjugated.

Supplier: STEMCELL Technologies

Rat monoclonal IgG2a antibody against human, mouse, cat CD45R (B220), unconjugated.

Supplier: STEMCELL Technologies

Rat monoclonal IgM antibody against mouse CD49b (integrin α2), unconjugated.

Supplier: STEMCELL Technologies

Animal component-free DNase I for digestion of DNA.

Supplier: STEMCELL Technologies

Interleukin 5 (IL-5) is a member of the short-chain 4-α-helical bundle subset of hematopoietic cytokines. It binds to the specific α receptor, which in turn recruits the common β receptor that initiates signaling via JAK/STAT and MAPK pathways. IL-5 is produced by Th2 cells, eosinophils, activated mast cells, and ILC2 cells. IL-5 affects the differentiation, activation, and survival of eosinophils, thus playing an important role in allergic inflammation, asthma, and parasite immunity. Stimulation of eosinophils with IL-5 leads to their activation, upregulation of CD11b expression, and inhibition of apoptosis (Shearer).

Supplier: STEMCELL Technologies

Mouse monoclonal IgG2a antibody against human, mouse, rat beta-tubulin III, Alexa Fluor® 488-conjugated.

Supplier: STEMCELL Technologies

Rat monoclonal IgG2a antibody against mouse CD4, PerCP-Cy5.5-conjugated.

Supplier: STEMCELL Technologies

Interleukin 3 (IL-3) is a species-specific pleiotropic cytokine that promotes the survival and proliferation of pluripotent hematopoietic stem cells and lineage-committed progenitor cells and their differentiation into mature cells of most lineages, including basophils, neutrophils, eosinophils, macrophages, dendritic cells, erythrocytes, and megakaryocytes (Yang et al.; Dorssers et al.; Broughton et al.). IL-3 is produced by activated T cells and has a physiological role in inflammation and allergies by promoting the secretion of inflammatory mediators such as histamine, IL-4, and IL-6 by basophils and eosinophils (Broughton et al.). The IL-3 receptor consists of a unique alpha subunit (CD123) and a beta common subunit (βc or CD131) that is shared with the receptors for IL-5 and GM-CSF, and is the principal signal transduction subunit for these cytokines. IL-3 binding to the heterodimeric receptor activates JAK/STAT, MAPK, and PI3K signaling pathways (Woodcock et al.).

Supplier: STEMCELL Technologies

Granulocyte-macrophage colony-stimulating factor (GM-CSF) promotes the proliferation and differentiation of hematopoietic progenitor cells and the generation of neutrophils, eosinophils, and macrophages. In synergy with other cytokines such as stem cell factor, IL-3, erythropoietin, and thrombopoietin, it also stimulates erythroid and megakaryocyte progenitor cells (Barreda et al.). GM-CSF was first purified from the culture of mouse lung tissue after lipopolysaccharide treatment. GM-CSF is produced by multiple cell types, including stromal cells, Paneth cells, macrophages, dendritic cells (DCs), endothelial cells, smooth muscle cells, fibroblasts, chondrocytes, and Th1 and Th17 cells (Francisco-Cruz et al.). The receptor for GM-CSF (GM-CSFR) is composed of two subunits: the cytokine-specific α subunit (GMRα; CD116) and the common subunit βc (CD131) shared with IL-3 and IL-5 receptors (Broughton et al.). GM-CSFR is expressed on hematopoietic cells, including progenitor cells and immune cells, as well as non-hematopoietic cells. GM-CSF is able to stimulate the development of DCs that ingest, process, and present antigens to the immune system (Francisco-Cruz et al.).

Supplier: STEMCELL Technologies

Mouse monoclonal IgG2b antibody against human OCT4 (OCT3), unconjugated.

Supplier: STEMCELL Technologies

Mouse monoclonal IgG2a antibody against mouse NK1.1 (CD161), PerCP-Cy5.5-conjugated.

Supplier: STEMCELL Technologies

Methylcellulose-based medium with EPO for human cells.

Supplier: STEMCELL Technologies

Integrated workflow containing tools to isolate and expand CD34+ progenitor cells from peripheral blood and their subsequent reprogramming to iPS cells.

Supplier: STEMCELL Technologies

Methylcellulose-based medium without cytokines for human cells.

Supplier: STEMCELL Technologies

RPMI 1640 medium.

Supplier: STEMCELL Technologies

Immunomagnetic isolation of untouched human cells

Supplier: STEMCELL Technologies

Animal component-free medium for freezing ES and iPS cells as single cells.

Supplier: STEMCELL Technologies

Supplement for expansion of mouse and rat neural stem and progenitor cells.

Supplier: STEMCELL Technologies

Pre-aliquoted methylcellulose-based medium with recombinant cytokines for human cells. 24x3ml vials.

Supplier: STEMCELL Technologies

Minimum Essential Medium Eagle - Alpha modification (Alpha MEM) with nucleosides.

Supplier: STEMCELL Technologies

Enzymatic cell dissociation reagent.

Supplier: STEMCELL Technologies

Rat monoclonal IgG2b antibody against mouse TER119, APC-conjugated.

Supplier: STEMCELL Technologies

Mouse monoclonal IgG2b, kappa isotype control antibody, PerCP-Cy5.5-conjugated.

Supplier: STEMCELL Technologies

Rat monoclonal IgG1 antibody against human, mouse, dog E-cadherin (CD324), unconjugated.

Supplier: STEMCELL Technologies

Defined, serum-free medium for neural induction of human ES and iPS cells.

Supplier: STEMCELL Technologies

Immunomagnetic positive selection of CD8a+ cells from mouse splenocytes or other tissues.