2779 Results for: "STEMCELL Technologies"

Supplier: STEMCELL Technologies

Mouse monoclonal IgG1 antibody against human CD34, Alexa Fluor® 488-conjugated.

Supplier: STEMCELL Technologies

Mouse monoclonal IgG1 antibody against human, chimpanzee CD45, APC-conjugated.

Supplier: STEMCELL Technologies

Mouse monoclonal IgG1 antibody against human, rhesus, cynomolgus CD5, PE­conjugated.

Supplier: STEMCELL Technologies

Immunodensity isolation of untouched circulating tumor cells.

Supplier: STEMCELL Technologies

Immunodensity depletion of lineage positive cells from cord blood.

Supplier: STEMCELL Technologies

Immunomagnetic isolation of untouched rat CD4+ T cells

Supplier: STEMCELL Technologies

Mouse monoclonal IgG1 antibody against dextran, FITC-conjugated.

Supplier: STEMCELL Technologies

Rat monoclonal IgG2b antibody against mouse EPCR (CD201), FITC­conjugated.

Supplier: STEMCELL Technologies

Serum-free neurophysiological basal medium for improved neuronal function.

Supplier: STEMCELL Technologies

Vascular endothelial growth factor (VEGF) is a heparin-binding homodimeric glycoprotein involved in vasculogenesis and angiogenesis. VEGF binds to FLT1 (VEGFR-1) and KDR (VEGFR-2), and activates Raf/MEK/ERK and PI3K/AKT pathways (Ferrara et al.). VEGF exists in multiple isoforms that result from alternative splicing of VEGF mRNA in the terminal exon. Proximal splice-site selection in exon 8 results in pro-angiogenic VEGFxxx isoforms (xxx is the number of amino acids), whereas distal splice-site selection results in anti-angiogenic VEGFxxxb isoforms (Nowak et al.). VEGF plays an important role in neurogenesis both in vitro and in vivo (Storkebaum et al.). It has neurotrophic effects on neurons of the central nervous system, and it promotes growth and survival of dopaminergic neurons and astrocytes. VEGF also promotes growth and survival of vascular endothelial cells, monocyte chemotaxis, and colony formation by granulocyte-macrophage progenitor cells (Ferrara et al.). Various splice variants of VEGF exist, with different functions. For example, it has been shown that VEGF isoform VEGF-164(165) and not VEGF-120(121) induces inflammation, stimulates intracellular adhesion molecule (ICAM)-1 expression on endothelial cells, and induces chemotaxis of monocytes (Usui et al.).

Supplier: STEMCELL Technologies

Granulocyte colony-stimulating factor (G-CSF) is a member of the CSF family of glycoproteins that regulate hematopoietic cell proliferation, differentiation, and function. It is a key cytokine involved in the production of neutrophils and the stimulation of granulocyte colony formation from hematopoietic progenitor cells (Metcalf andamp; Nicola). G-CSF causes a range of effects including a transient reduction of SDF-1 expression (Petit et al.), the activation of metalloproteases that cleave VCAM-1 (Levesque et al.), and the release of norepinephrine from the sympathetic nervous system (Katayama et al.), leading to the release or mobilisation of hematopoietic stem cells from the bone marrow into the periphery. The G-CSF receptor is expressed on a variety of hematopoietic cells, including myeloid-committed progenitor cells, neutrophils, granulocytes, and monocytes. In addition to hematopoietic cells, G-CSF is also expressed in cardiomyocytes, neuronal cells, mesothelial cells, and endothelial cells. Binding of G-CSF to its receptor leads to activation of the JAK/STAT, MAPK, PI3K, and AKT signal transduction pathways.

Supplier: STEMCELL Technologies

Rat monoclonal IgG2b antibody against mouse EPCR (CD201), biotin-conjugated.

Supplier: STEMCELL Technologies

Rat monoclonal IgG2a antibody against human, mouse F4/80, PerCP-Cy5.5-conjugated.

Supplier: STEMCELL Technologies

Rat monoclonal IgG2a antibody against mouse CD62L (L-selectin), PerCP-Cy5.5-conjugated.

Supplier: STEMCELL Technologies

Rat monoclonal IgG2a antibody against human, mouse F4/80, Alexa Fluor® 488-conjugated.

Supplier: STEMCELL Technologies

Rat monoclonal IgG2a antibody against mouse CD150 (SLAM), PE-Cyanine7-conjugated.

Supplier: STEMCELL Technologies

Methylcellulose-based medium without cytokines (including EPO) for mouse cells.

Supplier: STEMCELL Technologies

Rat monoclonal IgM antibody against mouse CD49b (integrin α2), Alexa Fluor® 488-conjugated.

Supplier: STEMCELL Technologies

Mouse monoclonal IgG1 antibody against human MUC1 (CD227), unconjugated.

Supplier: STEMCELL Technologies

Noggin binds to and antagonizes bone morphogenetic protein (BMP) ligands of the transforming growth factor beta (TGF-β) family. Noggin supports maintenance of undifferentiated human embryonic stem cells cultured in mouse embryonic fibroblast (MEF)-conditioned medium (Chaturvedi et al.), and promotes dopaminergic differentiation of embryonic stem cells and subsequent survival of dopamine neurons (Chiba et al.). Noggin is essential for development of ectodermal structures including neural tube, tooth, hair follicle, and eye, as well as patterning of mesodermal somites and skeletal structures. It also influences chondrogenesis, osteogenesis, and joint formation (Krause et al.).

Supplier: STEMCELL Technologies

For digestion of the extracellular matrix of cartilage.

Supplier: STEMCELL Technologies

Serum-free methylcellulose-based medium without cytokines for human cells.

Supplier: STEMCELL Technologies

Hamster (Armenian) monoclonal IgG antibody against mouse CD11c, PerCP-Cy5.5-conjugated.

Supplier: STEMCELL Technologies

Mouse monoclonal IgG1 antibody against rat NGFR/p75NTR (CD271), unconjugated.

Supplier: STEMCELL Technologies

Rat monoclonal IgG2a antibody against mouse Ly-6G, APC-conjugated.

Supplier: STEMCELL Technologies

McCoy's 5A medium.

Supplier: STEMCELL Technologies

Iscove's Modified Dulbecco's Medium (IMDM) with 25 mm HEPES.

Supplier: STEMCELL Technologies

Dulbecco's Modified Eagle's Medium (DMEM) with 4500 mg/l D-glucose.

Supplier: STEMCELL Technologies

Semi-solid methylcellulose-based medium for selection and cloning of cells.

Supplier: STEMCELL Technologies

Rat monoclonal IgM, kappa isotype control antibody, unconjugated.