"Other Essentials"

Supplier: Portwest

Seamless knitted nylon liners with polyurethane palm and finger coating. Ideal for intricate tasks where dexterity and breathability are essential.

Supplier: AAT Bioquest

DiI, DiO, DiD and DiR dyes are a family of lipophilic fluorescent stains for labeling membranes and other hydrophobic structures.

Supplier: AAT Bioquest

Digoxigenin (DIG)-conjugated horse radish peroxidase (HRP) is an excellent tool for biological detections with ELISA and other DIG-coupled assays.

Supplier: ProSci Inc.

IKK alpha Antibody: Nuclear factor kappa B (NF-kappa B) is a ubiquitous transcription factor and an essential mediator of gene expression during activation of immune and inflammatory responses. NF-kappa B mediates the expression of a great variety of genes in response to extracellular stimuli including IL-1, TNF alpha and bacteria product LPS. NF-kappa B is associated with I kappa B proteins in the cell cytoplasm, which inhibit NF-kappa B activity. The long-sought I kappa B kinase (IKK), which phosphorylates I kappa B, and mediates I kappa B degradation and NF-kappa B activation, was recently identified by several laboratories. IKK is a serine protein kinase, and the IKK complex contains alpha and beta subunits (IKK alpha and IKK beta ). IKK alpha and IKK beta interact with each other and both are essential for the NF-kappa B activation. IKK alpha specifically phosphorylates I kappa B-alpha. IKK alpha is expressed in a variety of human tissues.

Supplier: ProSci Inc.

IKK beta Antibody: Nuclear factor kappa B (NF-kappa B) is a ubiquitous transcription factor and an essential mediator of gene expression during activation of immune and inflammatory responses. NF-kappa B mediates the expression of a great variety of genes in response to extracellular stimuli including IL-1, TNF alpha , and bacteria product LPS. NF-kappa B is associated with I kappa B proteins in the cell cytoplasm, which inhibit NF-kappa B activity. The long-sought I kappa B kinase (IKK), which phosphorylates I kappa B, and mediates I kappa B degradation and NF-kappa B activation, was recently identified by several laboratories. IKK is a serine protein kinase, and the IKK complex contains alpha and beta subunits (IKK alpha and IKK beta ). IKK alpha and IKK beta interact with each other and both are essential for NF-kappa B activation. IKK beta phosphorylates both I kappa B-alpha and I kappa B-beta. IKK beta is expressed in variety of human tissues.

Supplier: MP Biomedicals

Rich medium for the growth of E. coli and certified for plasmid and other bacterial cultures in liquid medium.

Supplier: Abcam

Estrogen ELISA kit is a Quantitative ELISA kit for the measurement of Estrogen in plasma, Tissue Homogenate, serum, Other biological fluids samples.

Supplier: Abcam

Monkey IgM ELISA kit is a Sandwich (quantitative) ELISA kit for the measurement of Monkey IgM in Monkey in other biological fluids samples.

Supplier: ProSci Inc.

Serine kinase that plays an essential role in the NF-kappa-B signaling pathway which is activated by multiple stimuli such as inflammatory cytokines, bacterial or viral products, DNA damages or other cellular stresses. Acts as part of the canonical IKK complex in the conventional pathway of NF-kappa-B activation and phosphorylates inhibitors of NF-kappa-B on 2 critical serine residues. These modifications allow polyubiquitination of the inhibitors and subsequent degradation by the proteasome. In turn, free NF-kappa-B is translocated into the nucleus and activates the transcription of hundreds of genes involved in immune response, growth control, or protection against apoptosis. In addition to the NF-kappa-B inhibitors, phosphorylates several other components of the signaling pathway including NEMO/IKBKG, NF-kappa-B subunits RELA and NFKB1, as well as IKK-related kinases TBK1 and IKBKE. IKK-related kinase phosphorylations may prevent the overproduction of inflammatory mediators since they exert a negative regulation on canonical IKKs. Also phosphorylates other substrates including NCOA3, BCL10 and IRS1. Within the nucleus, acts as an adapter protein for NFKBIA degradation in UV-induced NF-kappa-B activation.

Supplier: Merck

Lactose monohydrate, powder, EMPROVE® EXPERT BP, Ph. Eur., JP, NF suitable for use as excipient, SAFC®

Supplier: Abcam

Selective TRPC4 channel blocker (IC₅₀ = 0,96 (fluorescence assay) - 2,6 μM (electrophysiological assay)). Selective versus TRPC6 (19-fold) and TRPC5 (9-fold). Essentially inactive at TRPV1, TRPV3, TRPA1 and TRPM8 channels at concentrations up to 22 μM.

Supplier: ProSci Inc.

ZFPM1 is a transcription regulator that plays an essential role in erythroid and megakaryocytic cell differentiation. ZFPM1 is an essential cofactor that acts via the formation of a heterodimer with transcription factors of the GATA family GATA1, GATA2 and GATA3. Such heterodimer can both activate or repress transcriptional activity, depending on the cell and promoter context. The heterodimer formed with GATA proteins is essential to activate expression of genes such as NFE2, ITGA2B, alpha- and beta-globin, while it represses expression of KLF1. ZFPM1 may be involved in regulation of some genes in gonads. ZFPM1 may also be involved in cardiac development, in a non-redundant way with ZFPM2/FOG2.

Supplier: Bioss

Essential for mesoderm formation and axial patterning during embryonic development.

Supplier: AAT Bioquest

Cy3® dye is one of the most common cyanine dyes used for labeling proteins, nucleic acids and other biological molecules.

Supplier: AAT Bioquest

SoNa™ 520 is a new sodium-sensitive fluorescent indicator dye used to detect sodium levels in cells and other biological samples.

Supplier: Sartorius

These qualitative filter papers are essentially used for analytical purposes and routine analyses, whenever no gravimetric analyses are required. They are wet-strengthened and can be used for pressure and vacuum filtration. They are made of refined pulp and linters with an >95% alpha-cellulose content, are very pure with an ash content <0,1%.