"Other Essentials"

Supplier: FUJIFILM WAKO CHEMICALS

Monothioglycerol (MTG) can be used as an alternative for 2-mercaptoethanol (2ME) since it exhibits comparable performance to 2ME when it is added to a medium in the culture of mouse ES D3 strain cells.

Supplier: Abcam

Anti-HIRA/HIR antibody [EPR25299-11] is a Rabbit Monoclonal antibody that is used in HIRA/HIR IHC-P, IP, Western Blot. Suitable for Human, Mouse, Rat samples. HIRA (Histone Cell Cycle Regulator) is a histone chaperone that facilitates replication-independent chromatin assembly by placing the variant histone H3.3 into nucleosomes. It plays a crucial role in the formation of senescence-associated heterochromatin foci (SAHF), which are involved in the irreversible cell cycle changes in senescent cells. Additionally, HIRA is essential for the periodic repression of histone gene transcription during the cell cycle.

Supplier: Cytiva

Capto™ HiRes Q and Capto™ HiRes S are prepacked columns for high-resolution purification of proteins and other biomolecules by ion exchange chromatography. They are well-suited for the preparation of highly pure proteins for structural studies and for protein analysis.

Supplier: PAN BIOTECH

Alpha MEM is a different formulation of MEM Eagle and contains a higher concentration of amino acids. It also has a higher concentration of lipoic acid, vitamins and pyruvate. Primarily it was developed for the cultivation of hamster kidney cells, but today it is used for a broad range of mammalian cells. Among others the alpha MEM promotes the growth and progeny of bone marrow cells in suspension culture and monolayer. A further possibility is the use as a separation medium or for the out-breeding of amniotic cells.

Supplier: Abcam

Anti-FAK (phospho Y397 + Y576 + Y925) antibody [RM1141] is a Rabbit Recombinant Multiclonal antibody that is used in FAK (phospho Y397 + Y576 + Y925) Dot Blot, Western Blot. Suitable for Human, Mouse, Rat samples. FAK (PTK2) is a non-receptor protein-tyrosine kinase which is involved in regulation of a number of essential cellular processes, including cell cycle progression, cell migration, actic cytoskeleton organisation and formation of focal adhesions. FAK is activated by phosphorylation and recruited to focal adhesions in response to integrin signalling. Aberrant expression of FAK may play a role in tumor formation, including ovarian, breast and non-small cell lung cancers.

Supplier: Abcam

Anti-CRBN antibody [EPR28739-64] is a Rabbit Monoclonal antibody that is used in CRBN Flow Cytometry (Intra), IP, Western Blot. Suitable for Human, Mouse samples. Cereblon (CRBN) is a multifunctional protein located in the cytoplasm, nucleus, and peripheral membranes of the human tissues. CRBN is closely related to the proliferation and metabolism of normal cells as well as tumor cells.It is part of the CRL4 CRBN ubiquitin E3 ligase complex, which is crucial for the action of immunomodulatory drugs (IMiDs) like lenalidomide and pomalidomide. These drugs bind to CRBN, leading to the degradation of transcription factors Ikaros and Aiolos, which are essential for myeloma cell survival. Additionally, novel cereblon E3 ligase modulators (CELMoDs) are being developed to overcome resistance to IMiDs, offering new therapeutic options for patients with CRBN mutation.

Supplier: Abcam

Anti-Fas antibody [EPR24898-74] is a Rabbit Monoclonal antibody that is used in Fas IHC-Fr, IHC-P, IP, Western Blot. Suitable for Mouse samples. FAS, also known as CD95 or APO-1, is a cell surface receptor that plays a significant role in regulating apoptosis (programmed cell death). FAS is crucial for inducing apoptosis in cancer cells. When FAS binds to its ligand (FASL), it triggers a cascade leading to cell death, which is essential for eliminating cancer cells.FAS was identified as an independent prognostic marker for recurrence free survival in breast cancer, with large variation in expression by receptor subtypes. Interestingly, the prognostic effect of CD8+ TILs in ER-negative disease was only valid for tumors with a high FAS expression.FAS expression might therefore act as a predictive factor for new emerging therapies.Researchers are exploring ways to enhance FAS signaling to prevent cancer relapse and improve the durability of immunotherapy responses.

Supplier: VWR Collection

PFAS PP short thread caps or PE snap ring caps, light green, with hole. White silicone/transparent polypropylene, for PFAS analysis.

Supplier: Abcam

Mouse Monoclonal CD18 antibody. Low endotoxin, Azide free. Suitable for IP, Flow Cyt, WB, FuncS and reacts with Human samples. Immunogen corresponding to Cell preparation containing ITGB2 protein.

Supplier: TEMPSHIELD

Hand protection for industrial settings working with LNG or liquid nitrogen.

Supplier: TEMPSHIELD

Waterproof Cryo-Grip® gloves offer improved grip on small objects while protecting hands and arms when working in hasardous, ultra-cold environments.

Supplier: Abcam

The DNA Concentrator Kit (ab156895) is a complete set of essential components which enables the experimenter to efficiently concentrate DNA from various DNA samples with low concentration of DNA including those from microdissection samples and paraffin-embedded tissues.

Supplier: Abcam

The DNA Isolation Kit-Urine (ab156899) is a complete set of essential components which enables the experimenter to efficiently isolate DNA from urine.

Supplier: THERMO SAVANT

The Thermo Scientific™ Savant™ SpeedVac™ SPD130DLX vacuum concentrator is a medium-capacity, vacuum concentrator with a modular design. It is compatible with a wide variety of solvents and offers resistance to TFA, DMSO, and other aggressive solvents used in combinatorial chemistry applications.

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Supplier: Thermo Fisher Scientific

The Pierce Glycoprotein Staining Kit is a convenient, fast, and sensitive colorimetric kit for staining glycosylated proteins in polyacrylamide gels or nitrocellulose membranes using the periodic acid-Schiff (PAS) method.

Supplier: Abcam

The PCR Clean-up Kit (ab156894) is a complete set of essential components which enables the experimenter to efficiently clean-up PCR products from various sources including conventional or real time thermal cycling PCR and isothermal gene amplification (PCR).