10503 Results for: "ENZO LIFE SCIENCES"
8-Bromoadenosine 3',5'-cyclic Monophosphothioate, Rp-Isomer sodium salt ≥99% (by HPLC)
Supplier: ENZO LIFE SCIENCES
Inhibitor of cAMP-dependent protein kinase (PKA), preferentially binding to type I PKA. Lipophilic analog of Rp-cAMPS. Resistant to mammalian cyclic nucleotide-dependent phosphodiesterases. Significantly more lipophilic and membrane permeant as compared to Rp-cAMPS or 8-Br-cAMP.
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12(S),20-Dihydroxyeicosa-5Z,8Z,10E,14Z-tetraenoic acid (DiHETE) ≥99% (by HPLC)
Supplier: ENZO LIFE SCIENCES
Arachidonic acid metabolite.
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Monastrol ≥98% (by TLC)
Supplier: ENZO LIFE SCIENCES
Cell permeable non-tubulin-interacting mitosis inhibitor. Blocks mitosis (IC50=14µM) by binding to the mitotic kinesin Eg5.
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Why Choose Corning Fetal Bovine Serum?
Our vertically integrated FBS serum supply chain, from collection to scientist, allows us to provide a consistent supply of FBS.
Anti-CYLD Rabbit Polyclonal Antibody
Supplier: ENZO LIFE SCIENCES
The tumor suppressor CYLD is a deubiquitinylating enzyme (DUB) that antagonises NF-κB and JNK signaling by disassembly of Lys63-linked ubiquitin chains synthesised in response to cytokine stimulation. The DUB activity of CYLD is mediated by its C-terminal ubiquitin specific protease (USP) domain, pathogenic truncations and mutations of which are associated with the hypertrophic skin tumor cylindromatosis through disruption of the USP domain and subsequent loss of CYLD catalytic activity.
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Anti-MRP1 Mouse Monoclonal Antibody
Supplier: ENZO LIFE SCIENCES
Host: Mouse, Isotype: IgG1
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Human recombinant HOP (from E. coli)
Supplier: ENZO LIFE SCIENCES
Produced in E. coli.
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3,5,7,4'-Tetrahydroxy-3'-methoxyflavone ≥98% (by HPLC)
Supplier: ENZO LIFE SCIENCES
Antitumor agent.
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2',5'-Dideoxyadenosine ≥98% (by TLC)
Supplier: ENZO LIFE SCIENCES
Adenylate cyclase inhibitor
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Anti-LAG3 Mouse Monoclonal Antibody
Supplier: ENZO LIFE SCIENCES
The lymphocyte activation gene-3 (LAG-3, CD223), a member of the immunoglobulin superfamily (IgSF) related to CD4, binds to the major histocompatibility complex (MHC) class II molecules but with higher affinity than CD4. Several alternative mRNA splice-variants of human LAG-3 have been described, two of them encoding potential secreted forms: LAG-3V1 (i.e. the D1-D2 domains of the protein, 36 kDa) and LAG-3V3 (D1-D3, 52 kDa). The longer form was detected by ELISA in the serum of healthy individuals as well as of tuberculosis patients with a favorable outcome. LAG-3 expression by T cell clones correlated with IFN-γ production, and hence soluble LAG-3 has been suggested as a serological marker of Th1 responses.
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Anti-SHC1 Mouse Monoclonal Antibody
Supplier: ENZO LIFE SCIENCES
Host: Mouse, Isotype: IgG1
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Bovine native Ganglioside GT1b . trisodium salt (from Brain)
Supplier: ENZO LIFE SCIENCES
Prevents neurotoxicity of glutamate on neuronal cells.
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4-Hydroxybenzylidenemalononitrile ≥98% (by TLC)
Supplier: ENZO LIFE SCIENCES
The tyrphostins are well known tyrosine kinase inhibitors. However, tyrphostin 8 has been shown to inhibit calcineurin (IC50=21 µM) while displaying weak inhibition of EGFR tyrosine kinase (IC50=560 µM).
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Proteasome 20S Assay Kit
Supplier: ENZO LIFE SCIENCES
A QuantiZyme™ Assay System. Fluorogenic, non-radioactive assay designed to measure chymotrypsin-like protease activity of purified 20S proteasome. This 96-well assay is useful for screening inhibitors and modulators of the 20S proteasome.
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Matrix Metalloproteinase-7 (MMP-7) fluorometric drug discovery kit
Supplier: ENZO LIFE SCIENCES
A QuantiZyme™ Assay System. The MMP-7 Fluorometric (also known as fluorimetric) Drug Discovery Kit is a complete assay system designed to screen inhibitors of matrix metalloproteinase-7 (MMP-7, matrilysin) using a quenched fluorogenic peptide: OmniMMP™ fluorogenic substrate Mca-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH. Mca fluorescence is quenched by the Dpa group until cleavage by MMPs at the Gly-Leu bond separates the two moieties.
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Clozapine ≥99% (by HPLC)
Supplier: ENZO LIFE SCIENCES
Dopamine receptor and serotonin receptor antagonist.
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Human recombinant KillerTRAIL™ (soluble) (from E. coli)
Supplier: ENZO LIFE SCIENCES
Produced in E. coli. The extracellular domain of human TRAIL (aa 95-281) is fused at the N-terminus to a His-tag and a linker peptide.
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Anti-DopamineR D2 Rabbit Polyclonal Antibody
Supplier: ENZO LIFE SCIENCES
Dopamine is the predominant catecholamine neurotransmitter in the mammalian brain, where it regulates locomotor, emotional, memory, and dietary intake functions, as well as peripheral roles such as hormone secretion and renal function. Dopamine receptors (D1-D5) are members of the seven transmembrane domain containing GPCR family, and are the target of several anti-psychosis and anti-Parkinsonian drugs. The D2, D3, and D4 receptors signal via coupling of Gi/Go alpha G-protein subunits to inhibit adenylyl cyclase activity and modulate cellular potassium and calcium ion channel conductance. Expression of the D2 receptor is found primarily in the brain (striatum, olfactory tubercle, and nucleus accumbens) and in the anterior and intermediate lobes of the pituitary.
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Anti-ADIPOR1 Goat Polyclonal Antibody
Supplier: ENZO LIFE SCIENCES
Host: Goat
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Extraction reagents
Supplier: ENZO LIFE SCIENCES
Concentrated lysis buffer for preparation of cell and tissue extracts.
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Anti-VIPERIN Rabbit Polyclonal Antibody
Supplier: ENZO LIFE SCIENCES
Viperin has been identified as a human cytomegalovirus and IFN-γ inducible protein. Its expression is activated by both TLR3-dependent and RIG-I-dependent pathways. Viperin inhibits influenza A virus release of infected cells by altering plasma membrane fluidity and the formation of lipid rafts. It acts on the lipid rafts by decreasing the activity of the enzyme farnesyl diphosphate synthase (FPPS) which is essential for isoprenoid biosynthesis.
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Fluorescein-12-ddUTP
Supplier: ENZO LIFE SCIENCES
Fluorescein-12-ddUTP can be used for 3’-end labeling of oligodeoxynucleotides using terminal transferase. It also serves as a substrate for E.coli DNA Polymerase I (holoenzyme and Klenow fragment), T4 and T7 DNA polymerases, Taq DNA polymerase and reverse transcriptase. Oligonucleotide probes labelled with fluorescein-12-ddUTP can be detected by direct fluorescence detection (green fluorescence) or by methods using horseradish peroxidase- or alkaline phosphatase-linked anti-fluorescein antibodies.
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CDK5 substrate
Supplier: ENZO LIFE SCIENCES
This peptide, PKTPKKAKKL, is derived from histone H1 and is a substrate for CDK5.
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Rufloxacin ≥98%
Supplier: ENZO LIFE SCIENCES
Fluoroquinolone antibacterial agent. Structurally similar to ofloxacin (Prod. No. ALX-380-297). Specific inhibitor of bacterial DNA gyrase (topoisomerase). Inhibits B-cell differentiation. Shows photosensitizing effects.