623 Results for: "Cy5-SSL-NHS ester&amp"

Supplier: Apollo Scientific

m-PEG16-NHS ester 250mg pack 1 * 250 mg

Supplier: Apollo Scientific

3-(2-Bromoacetamido)propanoic acid nhs ester 1g pack 1 * 1 g

Supplier: Merck

LC-SMCC is a heterobifunctional crosslinker with N-hydroxysuccinimide (NHS) ester and maleimide groups that allow covalent conjugation of amine- and sulfhydryl-containing molecules. NHS esters react with primary amines at pH 7-9 to form amide bonds, while the maleimides react with sulfhydryl groups at pH 6.5-7.5 to form stable thioether bonds. In aqueous solutions, hydrolytic degradation of the NHS ester is a competing reaction whose rate increases with pH. The maleimide group is more stable than the NHS-ester group but will slowly hydrolyze and also lose its reaction specificity for sulfhydryls at pH values greater than 7.5. For these reasons, conjugation experiments involving this type of heterobifunctional crosslinker are usually performed at pH 7.2-7.5, with the NHS-ester (amine-targeted) reaction being accomplished before or simultaneous with the maleimide (sulfhydryl-targeted) reaction

Supplier: Thermo Fisher Scientific

Thermo Scientific Pierce SMCC is a hetero-bifunctional crosslinker that contain N-hydroxysuccinimide (NHS) ester and maleimide groups that allow covalent conjugation of amine- and sulfhydryl-containing molecules. NHS esters react with primary amines at pH 7–9 to form amide bonds, while maleimides react with sulfhydryl groups at pH 6.5–7.5 to form stable thioether bonds. In aqueous solutions, NHS ester hydrolytic degradation is a competing reaction whose rate increases with pH. The maleimide group is more stable than the NHS-ester group, but will slowly hydrolyze and lose its reaction specificity for sulfhydryls at pH values > 7.5. For these reasons, conjugations with these crosslinkers are usually performed at pH 7.2–7.5, with the NHS ester (amine-targeted) reacted before or simultaneous with the maleimide (sulfhydryl-targeted) reaction.

Supplier: Apollo Scientific

m-PEG24-NHS ester 50mg pack 1 * 50 mg

Supplier: Apollo Scientific

m-PEG12-NHS ester 250mg pack 1 * 250 mg

Supplier: Apollo Scientific

m-PEG3-NHS ester 250mg pack 1 * 250 mg

Supplier: Apollo Scientific

m-PEG24-NHS ester 250mg pack 1 * 250 mg

Supplier: Thermo Fisher Scientific

Thermo Scientific Pierce SMCC is a hetero-bifunctional crosslinker that contain N-hydroxysuccinimide (NHS) ester and maleimide groups that allow covalent conjugation of amine- and sulfhydryl-containing molecules. NHS esters react with primary amines at pH 7–9 to form amide bonds, while maleimides react with sulfhydryl groups at pH 6.5–7.5 to form stable thioether bonds. In aqueous solutions, NHS ester hydrolytic degradation is a competing reaction whose rate increases with pH. The maleimide group is more stable than the NHS-ester group, but will slowly hydrolyze and lose its reaction specificity for sulfhydryls at pH values > 7.5. For these reasons, conjugations with these crosslinkers are usually performed at pH 7.2–7.5, with the NHS ester (amine-targeted) reacted before or simultaneous with the maleimide (sulfhydryl-targeted) reaction.

Supplier: Merck

SMPH is a heterobifunctional crosslinker with N-hydroxysuccinimide (NHS) ester and maleimide groups that allow covalent conjugation of amine- and sulfhydryl-containing molecules. NHS esters react with primary amines at pH 7-9 to form amide bonds, while the maleimides react with sulfhydryl groups at pH 6.5-7.5 to form stable thioether bonds. In aqueous solutions, hydrolytic degradation of the NHS ester is a competing reaction whose rate increases with pH. The maleimide group is more stable than the NHS-ester group but will slowly hydrolyze and also lose its reaction specificity for sulfhydryls at pH values greater than 7.5. For these reasons, conjugation experiments involving this type of heterobifunctional crosslinker are usually performed at pH 7.2-7.5, with the NHS-ester (amine-targeted) reaction being accomplished before or simultaneous with the maleimide (sulfhydryl-targeted) reaction.

Supplier: Apollo Scientific

Propargyl-PEG5-NHS ester 50mg pack 1 * 50 mg

Supplier: Apollo Scientific

Fmoc-PEG12-NHS ester 250mg pack 1 * 250 mg

Supplier: Apollo Scientific

Bis-PEG5-NHS ester 250mg pack 1 * 250 mg

Supplier: Apollo Scientific

Bis-PEG4-NHS ester 250mg pack 1 * 250 mg

Supplier: Apollo Scientific

Chloroacetamido-PEG4- NHS ester 250mg pack 1 * 250 mg

Supplier: Apollo Scientific

Biotin-PEG2-NHS ester 100mg pack 1 * 100 mg

Supplier: Apollo Scientific

Fmoc-PEG8-NHS ester 250mg pack 1 * 250 mg

Supplier: Apollo Scientific

Biotin-PEG3-NHS ester 100mg pack 1 * 100 mg

Supplier: Apollo Scientific

Bis-PEG7-NHS ester 50mg pack 1 * 50 mg

Supplier: Merck

EMCS and its water-soluble analog Sulfo-EMCS are heterobifunctional cross-linkers that contain N-hydroxysuccinimide (NHS) ester and maleimide groups that allow covalent conjugation of amine- and sulfhydryl-containing molecules. NHS esters react with primary amines at pH 7-9 to form amide bonds, while maleimides react with sulfhydryl groups at pH 6.5-7.5 to form stable thioether bonds. In aqueous solutions, hydrolytic degradation of the NHS ester is a competing reaction whose rate increases with pH. The maleimide group is more stable than the NHS-ester group but will slowly hydrolyze and also lose its reaction specificity for sulfhydryls at pH values > 7.5. For these reasons, conjugation experiments involving these cross-linkers are usually performed at pH 7.2-7.5, with the NHS-ester (amine-targeted) reaction being accomplished before or simultaneous with the maleimide (sulfhydryl-targeted) reaction.

Supplier: Apollo Scientific

Biotin-PEG8-NHS ester 100mg pack 1 * 100 mg

Supplier: Apollo Scientific

DNP-PEG4-NHS ester 250mg pack 1 * 250 mg

Supplier: Apollo Scientific

Thalidomide-O-PEG2-NHS ester 50mg pack 1 * 50 mg

Supplier: Apollo Scientific

Butyric acid nhs ester 250mg pack 1 * 250 mg

Supplier: Apollo Scientific

Butyric acid nhs ester 100mg pack 1 * 100 mg

Supplier: Apollo Scientific

Ald-PEG4-NHS ester 250mg pack 1 * 250 mg

Supplier: Apollo Scientific

Bis-PEG1-NHS ester 250mg pack 1 * 250 mg

Supplier: Apollo Scientific

Mal-PEG3-NHS ester 250mg pack 1 * 250 mg

Supplier: Apollo Scientific

Fmoc-PEG6-NHS ester 50mg pack 1 * 50 mg

Supplier: Apollo Scientific

Thalidomide-O-PEG2-NHS ester 25mg pack 1 * 25 mg