Collagenase Type III
For digestion of native collagen fibrils.
- Use in a variety of cell and tissue types
Digest native collagen fibrils in connective tissues with Collagenase Type III, sourced from Clostridium histolyticum. Collagenase preparations typically contain the activity of several proteases, including collagenase, caseinase, clostripain, and trypsin (Kessler and Yaron). While Collagenase Type III is lower in secondary proteolytic activity (caseinase, clostripain, and trypsin), it has similar collagenolytic activity compared to other collagenase types. Collagenase Type III has been used for the digestion of many tissues and cell types, including mammary glands (Rønnov-Jessen et al.), colon cancer stem cells (Prince et al.), and breast epithelial tumor cells (Chan et al.).
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- Species:Non-human primateHumanRatMouse