About this item
Mouse monoclonal IgG1 antibody against human, rhesus, cynomolgus CD5, PEconjugated.
- T cells
The UCHT2 antibody reacts with CD5, an ~67 kDa single-chain type I glycoprotein and member of the scavenger receptor superfamily, which is constitutively expressed on thymocytes, T cells, B cell subsets, peripheral blood dendritic cells and some leukemia and lymphoma cells, including chronic B lymphocytic leukemia (B-CLL) cells. CD5 is expressed at low levels on thymocytes and at high density on mature T cells. Putative ligands include CD5L and CD72. CD5 modulates T and B cell receptor signaling, thymocyte maturation, and T cell/B cell interactions via its physical and functional associations with the T cell receptor/CD3 complex and the B cell receptor. Studies with CD5 knockout mice indicate that CD5 negatively regulates antigen receptor-mediated signaling in thymocytes and mature T cells. The UCHT2 antibody binds to epitope 2 located in the extracellular domain of CD5.
Type:
Antigen: CD5
Clonality: Monoclonal
Clone: UCHT2
Conjugation: PE
Epitope:
Host: Mouse
Isotype: IgG1 kappa
Reactivity: Capuchin monkey;Chimpanzee;Common marmoset;Cynomolgus monkey;Human;Owl monkey;Rhesus monkey
Specifications
- Catalog No:
- STMC60082PE.1
- STMC60082PE
- Antigen name:
- CD5
- CD5
- Clonality:
- Monoclonal
- Monoclonal
- Conjugation:
- PE (Phycoerythrin)
- PE (Phycoerythrin)
- Clone:
- UCHT2
- UCHT2
- Reactivity:
- Capuchin monkey, Cynomolgus monkey, Common marmoset, Rhesus monkey, Chimpanzee, Human, Owl monkey
- Capuchin monkey, Cynomolgus monkey, Common marmoset, Rhesus monkey, Chimpanzee, Human, Owl monkey
- Host:
- Mouse
- Mouse
- Gene ID:
- 921
- 921
- Isotype:
- IgG1 kappa
- IgG1 kappa