Maturation kit for the generation of astrocytes from human ES and iPS cell-derived astrocyte precursors.

STEMdiff™ Astrocyte Maturation Kit is used to rapidly and efficiently generate cortical-type astrocytes from astrocytic precursors derived from human pluripotent stem cells (hPSCs) using the STEMdiff™ Astrocyte Differentiation Kit. Using this system, a highly pure population of astrocytes (an average of >70% S100B-positive and >60% GFAP-positive astrocytes; <15% doublecortin-positive neurons) can be generated from hPSCs in as few as 7 weeks and can be maintained long term in culture. Cells derived using these products are versatile tools for modeling human neurological development and disease, drug screening, toxicity testing, and cell therapy validation.