Specifications
- Antibody type:Primary
- Antigen name:CD3 antigen, epsilon polypeptide
- Antigen symbol:Cd3e
- Clonality:Monoclonal
- Clone:145-2C11
- Conjugation:FITC (Fluorescein Isothiocyanate)
- Flow cytometry:Yes
- Host:Hamster
- Isotype:IgG
- Cross adsorption:No
- Form:liquid
- Gene ID:P22646
- Antigen synonyms:Cd3e
- Storage buffer:Phosphate-buffered aqueous solution, ≤0,09% Sodium azide, may contain carrier protein/stabiliser, ph 7,2.
- Storage temperature:The product should be stored undiluted at 4 °C and should be protected from prolonged exposure to light. Do not freeze.
- Shipping temperature:4 °C
- Purification:The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.
- Pk:0,5 mg
Specifications
About this item
The 145-2C11 monoclonal antibody reacts with mouse CD3e, the 20 kDa epsilon chain of the TCR complex. Together with the gamma and delta subunits of CD3, the epsilon subunits are involved in the assembly, trafficking, and surface expression of T-cell receptor complex. CD3 is expressed on thymocytes, mature T cells, and natural killer T cells, and the epsilon chain enhances the antigen recognition.The 145-2C11 antibody binds to the TCR complex and, depending on the conditions, initiates T cells activation, proliferation, and apoptosis. The soluble antibody seems to block lysis of target cells by antigen-specific cytotoxic T lymphocytes. The 145-2C11 antibody does not cross-react with the rat leukocytes, and it is used as a phenotypic marker for mouse T lymphocytes.
Type: Primary
Antigen: Cd3e
Clonality: Monoclonal
Clone: 145-2C11
Conjugation: FITC (Fluorescein Isothiocyanate)
Epitope:
Host: Hamster
Isotype: IgG
Reactivity: Mouse