96-well membrane plates are designed for high throughput applications such as transport studies, tissue modeling, co-cultures, as well as migration and invasion assays.

• 96-well system for highthroughput applications
• Automation-friendly design
• High permeability and transparency for optimal diffusion rates and optical features
• Optimized fit for the prevention of media wicking
• Excellent membrane flatness for optimal and reproducible cell culture conditions
• Enlarged access ports – convenient access for pipettes, robots and TEER electrodes
• Sterile

The ThinCert 96-well HTS inserts offer a diverse selection of membrane specifications (pore size and density) within a 96 well format. The automation-friendly inserts are highly versatile and can be utilized for various applications such as transport, secretion, and diffusion studies, migration/invasion experiments, co-cultures, cytotoxicity tests, TEER measurements (Trans Epithelial Electric Resistance) and the generation of tissue models (e.g.,endothelia and epithelia).

The two-component system comprises a 96-well porous membrane plate manufactured entirely from polycarbonate (PC) and a corresponding polystyrene (PS) receiver plate. The tissue culture treated PC membrane allows for an ideal exchange of nutrients and substances, creating in vivo-like cultivation conditions to facilitate optimal cell growth, monolayer formation, and tissue differentiation.

The optimised ports ensure a convenient accessibility of the lower (basolateral) compartment with pipettes, automated liquid handling robots as well as electrodes for transepithelial electric resistance (TEER) measurements. The precise, well-centred fit of the membrane plate prevents wicking and provides stable and reproducible assay conditions.