Specifications
- Antibody type:Primary
- Antigen name:P38 MAPK
- Clonality:Polyclonal
- Conjugation:Alexa Fluor® 680
- Flow cytometry:Yes
- Host:Rabbit
- ImmunoChemistry:Yes
- ImmunoFluorescence:Yes
- Isotype:IgG
- Reactivity:Rabbit,Human,Rat,Mouse
- Western blot:Yes
- Epitope:141-240/360
- Form:Liquid
- Gene ID:1432
- Antigen synonyms:MAX-interacting protein 2|MAP kinase MXI2|p38ALPHA|Mxi2|MAPK14|CSAID-binding protein|MAPK 14|CSPB1|PRKM15|CSBP|MAP kinase p38 alpha|CSBP2|EXIP|Mitogen-activated protein kinase 14|p38|RK|Stress-activated protein kinase 2a|MAP kinase 14|CSBP1|PRKM14|SAPK2A|Mitogen-activated protein kinase p38 alpha|Cytokine suppressive anti-inflammatory drug-binding protein
- Modification:Unmodified
- Storage buffer:Aqueous buffered solution containing 0,01 M TBS (pH 7,4) with 1% BSA, 0,03% Proclin300 and 50% Glycerol
- Molecular weight:41 kDa
- Storage temperature:Store at –20 °C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Concentration:1 µg/µl
- Shipping temperature:4 °C
- Immunogen:KLH conjugated synthetic peptide derived from human P38MAPK
- Tested applications:ICC
- Purification:Purified by Protein A
- Pack type:Vial
- Pk:100 µl
Specifications
About this item
The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is activated by various environmental stresses and proinflammatory cytokines. The activation requires its phosphorylation by MAP kinase kinases (MKKs), or its autophosphorylation triggered by the interaction of MAP3K7IP1/TAB1 protein with this kinase. The substrates of this kinase include transcription regulator ATF2, MEF2C, and MAX, cell cycle regulator CDC25B, and tumor suppressor p53, which suggest the roles of this kinase in stress related transcription and cell cycle regulation, as well as in genotoxic stress response. Four alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.
Type: Primary
Antigen: P38 MAPK
Clonality: Polyclonal
Clone:
Conjugation: ALEXA FLUOR® 680
Public Immunogen Range: 141-240/360
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat, Rabbit, Others