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Anti-CDKN1A Thr57 Rabbit Polyclonal Antibody (Alexa Fluor® 750)
Anti-CDKN1A Thr57 Rabbit Polyclonal Antibody (Alexa Fluor® 750)
Catalog # BOSSBS-5238R-A750
Supplier:  Bioss
Anti-CDKN1A Thr57 Rabbit Polyclonal Antibody (Alexa Fluor® 750)
Catalog # BOSSBS-5238R-A750
Supplier:  Bioss

Specifications

  • Antibody type:
    Primary
  • Antigen name:
    CDKN1A Thr57
  • Clonality:
    Polyclonal
  • Conjugation:
    Alexa Fluor® 750
  • Host:
    Rabbit
  • ImmunoChemistry:
    Yes
  • ImmunoFluorescence:
    Yes
  • Isotype:
    IgG
  • Reactivity:
    Human,
    Rat,
    Mouse
  • Western blot:
    Yes
  • Form:
    Liquid
  • Gene ID:
    1026
  • Antigen synonyms:
    MDA-6|WAF1|P21|CAP20|p21CIP1|SDI1|Cyclin-dependent kinase inhibitor 1|CDK-interacting protein 1|MDA6|CDKN1A|CIP1|Melanoma differentiation-associated protein 6|CDKN1|PIC1
  • Modification:
    Phosphorylation (Thr57)
  • Storage buffer:
    Aqueous buffered solution containing 0,01 M TBS (pH 7,4) with 1% BSA, 0,03% Proclin300 and 50% Glycerol
  • Molecular weight:
    18 kDa
  • Storage temperature:
    Store at −20 °C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
  • Concentration:
    1 µg/µl
  • Shipping temperature:
    4 °C
  • Immunogen:
    KLH conjugated synthetic phosphopeptide derived from human CDKN1A around the phosphorylation site of Thr57 [TE(p-T)PL]
  • Tested applications:
    ICC
  • Purification:
    Purified by Protein A
  • Pack type:
    Vial
  • Pk:
    100 µl

Specifications

About this item

May be the important intermediate by which p53/TP53 mediates its role as an inhibitor of cellular proliferation in response to DNA damage. Binds to and inhibits cyclin-dependent kinase activity, preventing phosphorylation of critical cyclin-dependent kinase substrates and blocking cell cycle progression. Functions in the nuclear localization and assembly of cyclin D-CDK4 complex and promotes its kinase activity towards RB1. At higher stoichiometric ratios, inhibits the kinase activity of the cyclin D-CDK4 complex.

Type: Primary
Antigen: CDKN1A Thr57
Clonality: Polyclonal
Clone:
Conjugation: ALEXA FLUOR® 750
Public Immunogen Range:
Host: Rabbit
Isotype: IgG
Reactivity: Human; Mouse; Rat