PromoCell Mononuclear Cells (MNC) represent the lymphocyte and monocyte fraction isolated from umbilical cord blood or peripheral blood.

MNC are prepared by optimised low-density gradient centrifugation, which effectively reduces the granulocyte content. Red blood cells are gently but thoroughly depleted by proprietary techniques instead of osmotic lysis. This results in ultra-pure mononuclear cells with superior viability and unchanged biological function. In addition, the cells do not clump after thawing, allowing for easy handling and reproducible results.

MNC can be used directly for experiments or as a starting material for the isolation of several cell types, for example, hematopoietic and endothelial progenitors, monocytes, and lymphocyte subpopulations. Adult peripheral blood contains large numbers of mature immune cells but also some progenitor cells. Typical application fields are immunology, oncology, hematology, virology, and infection biology.