A Rapid, Quantitative and HTS‐compatible Live Cell Cytotoxicity Assay

• Assay includes unique drug-like dye that rapidly partitions into cells and labels acidic organelles
• Only commercial assay available that allows for long-term cell monitoring of cytotoxic effects
• Multi-well, high-throughput with rapid 10-15 minute dye incubation
• No co-incubation with artificial phospholipid analogs required for detection, eliminating the potential for confounding dye-associated artifacts
• Monitors lysosome accumulation as a response to prolonged drug treatment
• Quantitative results in as little as 3 hours, including drug treatment

96-well cell-based assay. Provides a rapid and quantitative approach for determining drug- or toxic agent-induced lysosome and lysosome-like organelle perturbations in live cells.