About this item
The caspases are a family of cysteine proteases that cleave after certain aspartate residues, and are primarily recognized as mediators of apoptosis. caspases are synthesized as inactive zymogens that can be cleaved to form active enzymes following the induction of apoptosis by stress or death receptors. Initiator caspases (e.g. caspase-8 and -10) are activated by dimerization of the zymogen on a dedicated adaptor protein. These activated initiator caspases in-turn cleave downstream effector or executioner caspases (e.g. caspase-3, -6, and -7) in a cascade-like manner, which cleave key cellular proteins that lead to the morphological changes associated with apoptotic cell death.
- For Western Blot
Recognizes human, mouse, rat, bovine, dog, chicken, guinea pig, hamster, monkey, pig, rabbit and yeast caspase-3. Detects a band of ~36kDa by Western blot.
Type: Primary
Antigen: CASP3
Clonality: Polyclonal
Clone:
Conjugation:
Epitope:
Host: Rabbit
Isotype:
Reactivity: Human
Specifications
- Catalog No:
- ENZOADIAAP113F
- ENZOADIAAP113D
- Antigen symbol:
- CASP3
- CASP3
- Antigen name:
- Caspase 3
- Caspase 3
- Antigen synonyms:
- caspase-3|procaspase3|caspase 3|protein Yama|CPP-32,PARP cleavage protease|Yama|cysteine protease CPP32|CASP-3|apoptosis-related cysteine protease|apopain|SREBP cleavage activity 1
- caspase-3|procaspase3|caspase 3|protein Yama|CPP-32,PARP cleavage protease|Yama|cysteine protease CPP32|CASP-3|apoptosis-related cysteine protease|apopain|SREBP cleavage activity 1
- Antibody type:
- Primary
- Primary
- Clonality:
- Polyclonal
- Polyclonal
- Reactivity:
- Human
- Human
- Host:
- Rabbit
- Rabbit
- Western blot:
- Yes
- Yes
- Form:
- Liquid. In PBS containing 50% glycerol and 0.09% sodium azide.
- Purification:
- Protein A affinity purified