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Human Recombinant CD137 (from HEK293 cells)
  PRSI90-252
 :  
Human Recombinant CD137 (from HEK293 cells)
  PRSI90-252
 :  

 

  • Pk:
    50 µG
  • Protein/peptide type:
    Recombinant
  • Source:
    HEK293 cells
  • Species:
    Human
  • Tag sequence:
    Fc Tag
  • Storage conditions:
    Stable for at least 6 months after receipt when stored at −20 °C.
  • Protein synonyms:
    TNFRSF9|4-1BB
  • Protein/peptide name:
    CD137
  • Purity:
    >95% (SDS-PAGE)
  • Sequence:
    1-186
  • Formulation:
    Lyophilized, Contains PBS.

 

 

CD137 (4-1BB) is a member of the tumor necrosis factor (TNF) receptor family. CD137 is expressed by activated T cells, dendritic cells, NK cells, granulocytes and cells of blood vessel walls at sites of inflammation. CD137 has costimulatory activity for activated T cells. Crosslinking of CD137 enhances T cell proliferation, IL-2 secretion survival and cytolytic activity. CD137 was shown to enhance immune activity to eliminate tumours in mice.

Fusion-Tag: Fc Tag

This recombinant proteins is for research use only.