Human recombinant IL12 p40 (from cells)
PRSI92-427
:
- Pk:50 µG
- Protein/peptide type:Recombinant
- Source:Cells
- Species:Human
- Storage conditions:Lyophilized protein should be stored at −20 °C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7 °C for 2-7 days. Aliquots of reconstituted samples are stable at −20 °C for 3 months.
- Protein synonyms:NK cell stimulatory factor chain 2|Interleukin-12 subunit beta|NKSF2|IL-12 subunit p40|CLMF p40|IL-12B|Cytotoxic lymphocyte maturation factor 40 kDa subunit|IL12B
- Protein/peptide name:IL12 p40
- Purity:> 95% as determined by reducing SDS-PAGE
- Molecular weight:34.6 kD
- Sequence:Ile23-Ser328
- Formulation:Lyophilized from a 0.2 um filtered solution of PBS,pH7.4. Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 ug/ml. Dissolve the Lyophilized protein in ddH2O. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
- Tested applications:Bioassay
Interleukin-12 subunit beta (IL-12B) belongs to the type I cytokine receptor family. It contains 1 fibronectin type-III domain and 1 Ig-like C2-type domain. IL-12B is a cytokine that acts on T and natural killer cells, and has a broad array of biological activities. IL-12 is a disulfide-linked heterodimer composed of the 40 kD cytokine receptor encoded by IL12B and a 35 kD subunit encoded by IL12A. IL12 is expressed by activated macrophages that serve as an essential inducer of Th1 cells development. It has been found to be important for sustaining a sufficient number of memory/effector Th1 cells to mediate long-term protection to an intracellular pathogen.
This recombinant protein can be used for biological assays. For research use only.