Specifications
- Antigen name:Protein Kinase AMP-activated Alpha 1 Catalytic Subunit
- Antigen symbol:PRKAA1
- Clonality:Polyclonal
- Conjugation:Unconjugated
- Host:Rabbit
- ImmunoChemistry:Yes
- Reactivity:Human,Rat,Mouse
- Western blot:Yes
- Form:Liquid
- Antigen synonyms:catalytic alpha-1 chain|catalytic|AMP-activated protein kinase|5'-AMP-activated protein kinase catalytic subunit alpha-1|AMPK|5'-AMP-activated protein kinase|tau-protein kinase PRKAA1|AMPK subunit alpha-1|AMPK alpha 1|AMP -activate kinase alpha 1 subunit|alpha-1|AMPKa1
- Concentration:1 mg/mL
- Immunogen:AMPKa1 (Ab-487) antibody was raised in was raised against a peptide sequence around aa.485~489 (S-G-S-V-S) derived from Human AMPKβ1.
- Size:100 µg
- Pk:100 µG
Specifications
About this item
Responsible for the regulation of fatty acid synthesis by phosphorylation of acetyl-CoA carboxylase. It also regulates cholesterol synthesis via phosphorylation and inactivation of hormone-sensitive lipase and hydroxymethylglutaryl-CoA reductase. Appears to act as a metabolic stress-sensing protein kinase switching off biosynthetic pathways when cellular ATP levels are depleted and when 5'-AMP rises in response to fuel limitation and/or hypoxia. This is a catalytic subunit.
Western Blot: 1:500~1:1000, Immunohistochemistry: 1:50~1:100
Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
Type:
Antigen: PRKAA1
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype:
Reactivity: Human, Mouse, Rat